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CPTAC

The study characterized aspects of the tumor immune landscape, including immunogenic alterations, neoantigens, and the immune microenvironment.

The 2010s saw major strides made through several large-scale initiatives aimed at mapping the human proteome and developing approaches for clinical work.

A survey asking researchers for their thoughts on the key developments in the field turned up applications ranging from clinical to structural.

The researchers combined genomic, transcriptomic, and proteomic profiling to gain insight into the basic biology and possible treatments for the disease. 

In a recent study, the researchers used the software to analyze multi-omic ovarian cancer data generated by the TCGA and CPTAC initiatives.

The DoD and VA-led initiative is moving beyond its initial focus on lung cancer to add analyses of multiple cancer types and a prospective, multisite study.

The ability to effectively use FFPE tissue opens up a large number of clinical samples for analysis, many with quality data on patient demographics, treatment, and outcomes.

The researchers used a combination of genomic, transcriptomic, and proteomic analyses to study mechanisms of resistance to the pan-PI3K inhibitor buparlisib.

Called LinkedOmics, the resource features three modules for analyzing multi-omic data collected in projects encompassing 11,158 patients and 32 cancer types.

The organization named the institutions that will be performing the proteomic and proteogenomic analyses planned to for the five-year, $65 million effort.

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Nature News reports that genomics is being applied to trace and try to prevent additional COVID-19 waves.

Rady's Children Hospital and San Diego County are teaming up to test pediatric patients and their families for COVID-19 to gauge the spread of the virus locally, according to the San Diego Union-Tribune.

Wildlife managers aim to boost the genetic diversity of Mexican gray wolves by placing captive-born foster pups into packs with similarly aged wild pups, the Mercury News reports.

In Science this week: Genetic Probability tool identifies likely diagnoses in 45 percent of inflammatory arthritis cases, and more.