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CPTAC

The study characterized aspects of the tumor immune landscape, including immunogenic alterations, neoantigens, and the immune microenvironment.

The 2010s saw major strides made through several large-scale initiatives aimed at mapping the human proteome and developing approaches for clinical work.

A survey asking researchers for their thoughts on the key developments in the field turned up applications ranging from clinical to structural.

The researchers combined genomic, transcriptomic, and proteomic profiling to gain insight into the basic biology and possible treatments for the disease. 

In a recent study, the researchers used the software to analyze multi-omic ovarian cancer data generated by the TCGA and CPTAC initiatives.

The DoD and VA-led initiative is moving beyond its initial focus on lung cancer to add analyses of multiple cancer types and a prospective, multisite study.

The ability to effectively use FFPE tissue opens up a large number of clinical samples for analysis, many with quality data on patient demographics, treatment, and outcomes.

The researchers used a combination of genomic, transcriptomic, and proteomic analyses to study mechanisms of resistance to the pan-PI3K inhibitor buparlisib.

Called LinkedOmics, the resource features three modules for analyzing multi-omic data collected in projects encompassing 11,158 patients and 32 cancer types.

The organization named the institutions that will be performing the proteomic and proteogenomic analyses planned to for the five-year, $65 million effort.

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Nature News writes that additional details about the UK plan for an agency to support high-risk, high-reward science are needed.

The New York Times reports that the US Food and Drug Administration has authorized Johnson & Johnson's SARS-CoV-2 vaccine.

The Wall Street Journal writes new studies are giving glimpses into the origins of SARS-CoV-2.

In PLOS this week: analysis of Plasmodium population structure, qPCR assay to diagnose scabies, and more.