Using a microfluidics-based single-cell isoform RNA-seq approach, researchers clustered cerebellar cells and saw isoforms with cell type-specific expression.
The consortium aims to identify tuberculosis protein targets and corresponding small molecule inhibitors that can be used to develop drugs to shorten therapy duration.
In PLOS this week: genetic factors influencing inorganic arsenic metabolism and toxicity, a germline variant in the cell adhesion molecule-coding gene DSCAM, and more.
