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Under the Genomic Translation for ALS Clinical Care project, the partners will perform next-generation sequencing and clinical phenotyping on 1,500 ALS patients.

Public health researchers argue in NEJM that precision medicine initiatives will take away from needed efforts to improve population health.

Scientists from Columbia University have developed a microfluidic device that can capture RNA from single cells on glass plates or beads.

A Columbia University team has retracted its integrative genomic analysis of Alzheimer's disease Nature paper due to research misconduct.

Mutations present in tissue from Barrett's esophagus may help predict progression to high-grade dysplasia or cancer.

Drug companies are rushing toward genomic databases to inform their searches for new drugs, Reuters reports.

Using chromosomal microarrays, a Columbia University Medical Center-led team identified large genomic imbalances in pediatric chronic kidney disease, linking them to other disorders.

With genotyping and retroelement insertion mapping, researchers identified a clonal form of leukemia that's transmitted horizontally between soft-shell clams.

Thirteen institutions and life sciences companies have teamed up to launch the free repository that will offer access to allele frequency information from genomes and exomes.

Exome sequence data for nearly 9,300 individuals pointed to new and known risk genes for sporadic ALS, including genes contributing to innate immunity and autophagy.

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Researchers tie a variant in ADAMTS3 to breathing difficulties in dissimilar dog breeds, according to Discover's D-brief blog.

The Japan Times reports that researchers sequenced the genome of a woman who lived during the Jomon period.

Parents of children with rare genetic disease have to contend with shifts in the interpretation of genetic variants, the Wall Street Journal reports.

In Science this week: single-nucleus RNA sequencing of brain tissue from individuals with autism, and more.