The partners aim to identify master regulators in the molecular networks of GIST patients that can serve as drug targets for existing treatments.
Heterozygous deletions at the chromosome 22q11.2 locus contribute to kidney problems in individuals with DiGeorge syndrome or congenital urogenital conditions.
The results suggest that targeted treatments used in rare epilepsies might also work in a portion of patients with common forms of the disease.
The software takes somatic mutation profiles from individual patients as input and uses them to prioritize relevant mutations and potential treatments.
Investigators will compare results using Biocept's platform in cerebrospinal fluid to current standard methods for diagnosing leptomeningeal metastases.
Under the PIPseq program, Columbia University researchers sequenced the exome, transcriptome, or a gene panel in tumors of 101 high-risk pediatric cancer patients.
The funding is part of the NHGRI Genome Technology Program, which promotes new methods, technology, and instruments for sequencing and functional genomics.
Seeq has much in common with DNA.Land, launched last year, but targets individuals who have not used services from direct-to-consumer testing companies
The Irving Institute, a CUMC partnership with New York-Presbyterian, will fund its precision medicine program and the development of new therapies.
Columbia University settles a civil fraud lawsuit that said it improperly used its on-campus indirect cost rate when seeking reimbursement for more than 400 grants.
The New York City Police Department will be removing DNA profiles from a local database if they are from people who were never convicted of a crime, the New York Times reports.
Science reports that accusations of sexual assault against a microbiome researcher has also led to questions about his academic certifications.
Wired reports that researchers are analyzing the DNA fish leave behind in water to study their populations.
In Science this week: comprehensive cellular map of the human thymus, evidence of admixture between the ancestors of Neanderthals and Denisovan and a 'superarchaic' population.