An analysis of post-mortem brain transcripts led to Alzheimer's-related alternative gene splicing and expression events, including those influenced by known risk alleles.
Over the next four years, researchers will aim to pinpoint the impact of personal genomic information given to patients with autism and their families.
A study found that cis-regulatory variation modifies the penetrance of coding variants, and that variants' regulatory haplotype configuration affects disease risk.
In Cell this week: structural variants affecting regulatory loci in prostate cancer, immune features in the breast cancer microenvironment, and more.
Researchers at Columbia University and CHOP believe they can shorten time to diagnosis and improve yield by extracting phenotypic data from EHRs for genomic labs.
In Science this week: genetic overlap among many psychiatric disorders, and more.
In Cell this week: interactions between malignant and immune cells in ovarian cancer, gene regulatory features in mouse macrophages, and more.
A Columbia University-led team used emergency contact information from medical records to create family trees and estimate disease heritability.
Science speaks with Columbia University's Yaniv Erlich about using genetic genealogical data to identify people.
A study in Microbiome finds that heavy drinkers have an unhealthy mix of bacteria in their mouths.
Nature News examines how science in the UK may fare as Boris Johnson, the next prime minister, pursues Brexit.
CNN reports that Immigration and Customs Enforcement in the US has expanded its DNA testing to seven sites along the southern border.
In PNAS this week: role for exosomes in neuronal circuit development, tuberculosis pathogen enzymes, and more.
Undoing Obamacare protections could affect people's willingness to undergo genetic testing, Sarah Lawrence College's Laura Hercher and the University of Iowa College of Law's Anya Prince write at BuzzFeed News.