Columbia

The PREDICT/PDF-2180 virus is the latest coronavirus identified in a bat species, supporting a potential bat reservoir role in the evolution of such viruses.

Columbia University researchers uncover a gene variant associated with differential aging in the brain after the age of 65.

Mutation and expression patterns in longitudinal, multifocal, and solitary tumor samples suggest glioblastoma follows a multiverse model of evolution.

The partners aim to identify master regulators in the molecular networks of GIST patients that can serve as drug targets for existing treatments.

Heterozygous deletions at the chromosome 22q11.2 locus contribute to kidney problems in individuals with DiGeorge syndrome or congenital urogenital conditions.

The results suggest that targeted treatments used in rare epilepsies might also work in a portion of patients with common forms of the disease.

The software takes somatic mutation profiles from individual patients as input and uses them to prioritize relevant mutations and potential treatments.

Investigators will compare results using Biocept's platform in cerebrospinal fluid to current standard methods for diagnosing leptomeningeal metastases.

Under the PIPseq program, Columbia University researchers sequenced the exome, transcriptome, or a gene panel in tumors of 101 high-risk pediatric cancer patients.

The funding is part of the NHGRI Genome Technology Program, which promotes new methods, technology, and instruments for sequencing and functional genomics.

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The Chan Zuckerberg Initiative is investing in Cold Spring Harbor Laboratory's BioRxiv.

A study appearing in PLOS One finds that shortened consent forms don't affect clinical trial participants' understanding of the study.

The National Security Agency monitored signal intelligence for signs of "nefarious" genetic engineering projects, Gizmodo reports.

In Nature this week: barley genome sequenced, method for genotyping and phasing short tandem repeats, and more.