Cleveland Clinic Alzheimer's Disease Genes, Treatment Targets Identified With Deep Learning Method Researchers discovered Alzheimer's risk genes and druggable targets based on protein interaction, gene network, functional genomic, expression, and health record data. Studies Unravel SARS-CoV-2 Protein Interactions With Human Proteins A pair of studies identified connections between proteins from SARS-CoV-2 and human cells, hitting on key host pathways and potential treatment targets. Cancer Centers Nudge Oncologists Toward DPYD Testing as PGx Supporters Push For Guidelines Change Premium Several institutions, swayed by PGx experts and advocates, are setting up DPYD testing to avoid deadly chemo toxicities in patients even though the NCCN and FDA don't back it. PTEN Mutation Syndrome Leads to Breast Cancers With Distinct Molecular Alterations A protein-coding sequence analysis uncovered somatic mutations that distinguished breast cancers in individuals with PTEN hamartoma tumor syndrome from sporadic breast cancers. Cleveland Clinic Gets FDA Emergency Use Authorization for Molecular COVID-19, Flu Combo Test The PCR-based test uses a previously authorized Roche SARS-CoV-2 and influenza assay in combination with a sample self-collection kit. Oct 13, 2021 FDA Grants EUAs for Cleveland Clinic COVID-19 PCR Test, Quest Diagnostics Sample Self-Collection Kit Sep 21, 2021 Personal Genome Diagnostics, Cleveland Clinic Join Forces to Advance Liquid Biopsy Aug 13, 2021 Amazon, Cleveland Clinic Get FDA Emergency Use Authorizations for SARS-CoV-2 Tests Jun 30, 2021 Recuro Health Enters Genomics Market With MyLegacy Purchase from Cleveland Clinic Premium Apr 26, 2021 Early Pandemic SARS-CoV-2 Clade Shift in Cleveland May Have Reduced Mortality, Study Suggests Apr 20, 2021 Prostate Cancer Study Shows Oncotype DX GPS Test Accurately Measures Long-Term Outcomes Premium Mar 30, 2021 Cleveland Clinic, IBM Partner on High-Performance Computing for Life Science, Healthcare Research Mar 2, 2021 PreludeDx DCIS Breast Cancer Test Helps Determine Radiation Therapy Benefits, Reduce Overtreatment Premium Feb 18, 2021 MSK Study Underscores Need to Validate Cancer-Specific Tumor Mutational Burden Cutoffs Premium Feb 18, 2021 Metabolon Strikes Biomarker Discovery Partnership With Cleveland Clinic Feb 8, 2021 Eurofins Viracor, Cleveland Clinic Sign License Deal for Kidney Transplant Rejection Biomarker Test Oct 14, 2020 Epigenomic Study of Brain Development Uncovers Cell Type-Specific Regulatory Programs Aug 5, 2020 Cleveland Clinic, Three Other Labs Get FDA EUAs for Coronavirus Tests Jul 1, 2020 Celsius Therapeutics Teams With Oxford, Cleveland Clinic, LMU on Single-Cell IBD Research May 6, 2020 Pediatric Cancer Patients With Solid Tumors Have Many Druggable Germline Alterations May 1, 2020 People in the News: Peter Meintjes, Timothy Chan, Satnam Alag, More Jan 31, 2020 Copy Number Variants May Influence Clinical Presentation Among Individuals with PTEN Mutations Jan 14, 2020 Asthma Drug Resistance Linked to Variant in Androgen Synthesis Gene Jul 24, 2019 Gray Foundation Awards $25M in Cancer Research Grants Apr 4, 2019 Shivom Partners With Cleveland Clinic Spinout Family Care Path Load More Breaking News Simple HealthKit Raises $8M in Series A Round Top Five Articles on GenomeWeb Last Week: Quantum-Si Layoffs, UBS Coverage Initiations, More LumiraDx Secures FDA Emergency Use Authorization, UK Approval for COVID-19, Flu Test Rarity Bioscience Raises Additional €500,000 Cancer Prognoses Informed by Module-Based Approach, Study Finds The Scan UK Team Presents Genetic, Epigenetic Sequencing Method Using enzymatic DNA preparation steps, researchers in Nature Biotechnology develop a strategy for sequencing DNA, along with 5-methylcytosine and 5-hydroxymethylcytosine, on existing sequencers. DNA Biobank Developed for French Kidney Donors, Recipients The KiT-GENIE biobank described in the European Journal of Human Genetics contains DNA samples, genotyping profiles, immune patterns, and clinical features for thousands of kidney donors or transplant recipients in Nantes, France. Cardiometabolic Disease May Have Distinct Associations With Microbial Metabolites in Blood, Gut By analyzing gut microbes in combination with related metabolites in feces and blood, researchers in Nature Communications found distinct cardiometabolic disease relationships at each site. Study Reveals New Details About Genetics of Major Cause of Female Infertility Researchers in Nature Medicine conducted a whole-exome sequencing study of mote than a thousand patients with premature ovarian insufficiency.