City of Hope

This Week in PNAS

In PNAS this week: analytical method for assessing shared variants, treatment targets in hereditary pancreatic cancer, and more.

In individuals diagnosed with prostate cancer before the age of 45, researchers saw enhanced expression of immune- and inflammation-related genes.

As part of the deal, TGen will also become a subsidiary of City of Hope's parent organization, but will remain a non-profit headquartered in Arizona.

Researchers will study how prior hypoglycemic episodes can result in the "metabolic memory" of persistent vascular complications.

CHICAGO (GenomeWeb News) – Researchers are tracking down genetic variants that they hope will help identify childhood cancer patients at increased risk of treatment-related health complications later in life, City of Hope researcher Smita Bhatia reported at the annual American Society of Clinical

NEW YORK (GenomeWeb) – Sangamo BioSciences today said that the California Institute for Regenerative Medicine has awarded $5.6 million grant to researchers at City of Hope to develop an HIV/AIDS therapeutic based on Sangamo's zinc finger nuclease genome editing technology.

The Biological Research Center of the Hungarian Academy of Sciences and Glaxo Group Limited, a subsidiary of GlaxoSmithKline, have been jointly awarded US Patent No. 8,389,802, "Artificial chromosomes, uses thereof, and methods for preparing artificial chromosomes.

City of Hope has been awarded US Patent No. 8,227,191, "Method for amplification and detection of RNA sequences."
George Murakawa, Bruce Wallace, John Zaia, and John Rossi are named as inventors on the patent.

Lawrence Livermore National Security has been awarded RE43,365, "Apparatus for chemical amplification based on fluid partitioning in an immiscible liquid." The patent is a reissuance of RE41,780 issued in September 2010, which itself was a reissuance of US Patent No.

The University of North Carolina at Chapel Hill has been awarded US Patent No. 8,148,511, "Methods and compositions for the detection and quantification of E. coli and Enterococcus."

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Helix customers can purchase apps that interpret different aspects of their genome, Technology Review reports.

The New York Times reports that a number of companies and research institutes are pursuing gene therapies.

Salmon with shorter telomeres survive to make the trip back to their river homes, New Scientist reports.

In PLOS this week: vaginal microbiome composition, population patterns of Chagas-carrying Rhodnius ecuadoriensis, and more.