Cincinnati Children's Hospital Gene Screening Tool Allows Researchers to Zero in on Variants Influencing Lupus Risk The variants also hinted that lupus risk may stem from changes to enhancer activity that affects transcription factor binding. Polygenic Risk Scores Provide Insights Into Drug-Related Liver Injury Using genome-wide association study, cell line, organoid, and other data, researchers tracked down polygenic contributors to drug-induced liver injury in hepatocytes. Risk-Assessment Phase of eMERGE Looks to Diversify Polygenic Risk Scoring Premium In the next round of the eMERGE program, NIH is supporting development of methodologies for integrating genotypic and phenotypic risk scoring into clinical care. Children's Hospital Network Wins $8.5M NIH Grant to Expand Data-Sharing Initiative The Genomics Research and Innovation Network has built an open-source system for querying genotype-phenotype databases at its member hospitals. Interoperability Network Helps Children's Hospitals Aggregate Genotype-Phenotype Data Premium The Genomics Research and Innovation Network (GRIN) is a federated platform from three major pediatric hospitals to assist in research and treatment of rare diseases. Aug 30, 2019 Medulloblastoma Single-Cell Study Yields Tumor-Initiating Cell Population Containing Outcome Clues Mar 28, 2019 New Consortium Outlines Vision for Pediatric Cell Atlas, Seeks Funding for Effort Premium Nov 27, 2018 Mitochondrial DNA Can Be Paternally Inherited in Humans, New Study Finds Nov 9, 2018 National Cancer Institute Awards $4M to Brain Tumor Sequencing Projects Oct 30, 2018 Circadian Phase Can Be Gleaned From Gene Expression Within Skin Cells Aug 16, 2018 Tufts Medical Center, Collaborators Win $8M NIH Grant to Study NGS in Newborns Apr 16, 2018 Epstein-Barr Virus Protein, Human Transcription Factors Implicated in Autoimmune Diseases Sep 18, 2017 Variant Reclassification Common, Causes Range of Emotions Among Patients Sep 14, 2016 MBio, Cincinnati Children's Hospital Collaborate on Septic Shock Panel for Clinical Dx Jul 6, 2016 Host Expression Signature Differentiates Bacterial, Viral Infections; May Lead to Dx Device Premium May 17, 2016 Cincinnati Children's Hospital Building Informatics Infrastructure to Target Rare Pediatric Diseases Premium Jan 12, 2016 Researchers Identify Molecular Target and Develop Experimental Treatment for Fanconi Anemia Jan 5, 2016 Cincinnati Children's Awarded $5.7M NIH Grant to Manage Pediatric Cardiovascular Disease Consortia Oct 27, 2015 Transcriptomic Analysis of Amniotic Fluid Uncovers Gene Expression Changes Linked to Fetal Maturity Aug 27, 2015 Cincinnati Children's Hospital Team Describes Clinical Exome Sequencing Experience Premium Apr 21, 2015 Genome-wide Analysis of Asthma Patients Implicates VNN1 Expression in Treatment Response Mar 24, 2015 NIH Awards CCHMC $2.2M to Develop Database of Rare Childhood Genetic Disorders Jul 17, 2014 Genomics in the Journals: Arrays 2014.07.17 Jul 10, 2014 Genomics in the Journals Jul 10, 2014 Apr 28, 2014 Diagnovus Reaches Deal to Commercialize EoE Assay Load More Breaking News Lunaphore Technologies, University of Bern Partner on Colorectal Cancer Study People in the News: New Appointments at Biocept, Novacyt, Centogene, Illumina, More In Brief This Week: Sophia Genetics, Twist Bioscience, Dante Labs, MGI, Codex DNA, More New Products Posted to GenomeWeb: SpeeDx, Bio-Techne, NuProbe, More DiaSorin Q2 Revenues Rise 20 Percent on SARS-CoV-2 Testing Demand Cepheid Gets $28M From BARDA for SARS-CoV-2 Tests The Scan Interfering With Invasive Mussels The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels. Participation Analysis A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports. Right Whales' Decline A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC. Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.