Close Menu

CHOP

Whole-exome sequencing shows that relapse in acute lymphoblastic leukemia is driven by cancer cells with sneakier, rather than more numerous, mutations.

Using a genome-wide association study approach, investigators at the Children's Hospital of Philadelphia and elsewhere have uncovered four new risk loci for an inflammatory food allergy condition called eosinophilic esophagitis.

NEW YORK (GenomeWeb) – Medgenics announced on Wednesday a collaboration with the Children's Hospital of Philadelphia to accelerate the development of new therapies for pediatric rare and orphan genetic diseases.

NEW YORK (Genomeweb) — A study comprehensively analyzing the genomes of more than 1,500 neuroblastoma cases has better determined the prognostic significance of ALK mutations and other alterations in neuroblastoma, and has biochemically investigated many of these variants to determine which ones

NEW YORK (GenomeWeb) – In the American Journal of Human Genetics, researchers from three consortia report a prominent role for de novo mutations in epileptic encephalopathies.

NEW YORK (GenomeWeb News) – A Children's Hospital of Philadelphia-led team has identified autism spectrum disorder-related changes in three interacting gene sets, spelling out details about the biological processes behind the neuropsychiatric conditions.

This article has been corrected to list all of the genes targeted by the assay. The previous version noted only one of them.

NEW YORK (GenomeWeb News) – The Penn Medicine/CHOP Friedreich's Ataxia Center of Excellence has been created with a $3.25 million gift from the Friedreich's Ataxia Research Alliance (FARA) in partnership with the Hamilton and Finneran families.

Pages

Nature News reports that genomics is being applied to trace and try to prevent additional COVID-19 waves.

Rady's Children Hospital and San Diego County are teaming up to test pediatric patients and their families for COVID-19 to gauge the spread of the virus locally, according to the San Diego Union-Tribune.

Wildlife managers aim to boost the genetic diversity of Mexican gray wolves by placing captive-born foster pups into packs with similarly aged wild pups, the Mercury News reports.

In Science this week: Genetic Probability tool identifies likely diagnoses in 45 percent of inflammatory arthritis cases, and more.