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Using genomic data for pediatric low-grade gliomas, researchers uncovered a MYB-QKI fusion that appears to drive angiocentric glioma development.

The Center for Data Driven Discovery in Biomedicine is a joint project of CHOP Research Institute and CHOP's Department of Biomedical Health and Informatics. 

The results showed that syndromic forms of autism are more likely when children have alterations of genes in the mGluR pathway.

Using genotyping data, the Children's Hospital of Philadelphia-led team found high heritability across pediatric-onset autoimmune diseases.

Through a meta-analysis of 10 pediatric-onset autoimmune diseases, Children's Hospital of Philadelphia researchers found 22 loci shared among the conditions.

The funding will support work identifying the mechanisms underlying the differential responses among pediatric and adult ALL patients to therapy.

A group of 10 so-called PediSeeker volunteers from the Children's Hospital of Philadelphia interpreted secondary variants in PediSeq exomes.

Whole-exome sequencing shows that relapse in acute lymphoblastic leukemia is driven by cancer cells with sneakier, rather than more numerous, mutations.

Using a genome-wide association study approach, investigators at the Children's Hospital of Philadelphia and elsewhere have uncovered four new risk loci for an inflammatory food allergy condition called eosinophilic esophagitis.

NEW YORK (GenomeWeb) – Medgenics announced on Wednesday a collaboration with the Children's Hospital of Philadelphia to accelerate the development of new therapies for pediatric rare and orphan genetic diseases.

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Researchers have sequenced the genome of the depth-dwelling giant squid.

Prosecutors have charged a former Drexel University professor with theft for allegedly spending federal grant money on adult entertainment and other unrelated expenses, according to the Philadelphia Inquirer.

 

Chris Collins, a former US representative, has been sentenced to more than two years in prison in an insider trading case involving an Australian biotechnology firm, the New York Times reports.

In PNAS this week: Trypanosoma brucei transcripts, estimate of people at risk of inherited retinal disease, and more.