CHOP
Childhood Acute Lymphoblastic Leukemia Subtypes, Prognostic Features Uncovered in Genomic Study
Researchers identified 15 subtypes of T-lineage ALL, along with mutation, expression, and regulatory shifts providing development and prognostic clues.
The method, designed for nanopore sequencing but compatible with other methods, could reduce the cost of studying RNA isoforms and splicing.
The centerpiece of the new features is Ready2Run, a collection of public and private genome analysis and interpretation pipelines that can be accessed through a single API call.
ACMG Issues Updated Practice Guidelines for Hearing Loss Evaluations
The update provides recommendations on how to approach genetic testing for individuals suspected of having syndromic or nonsyndromic hearing loss.
Sequencing-Based MRD Detection in Bone Marrow May Predict ALL Relapse After CAR T-Cell Therapy
Researchers looked at relapse-related markers over time in pediatric and young adult acute lymphoblastic leukemia patients after CAR T-cell treatment.