Chinese University of Hong Kong Hong Kong Team Develops Method to Improve PacBio Direct Cytosine Methylation Detection Premium The approach considers kinetic signals from the DNA polymerase used in PacBio sequencing, as well as the sequence context, to determine cytosine methylation sites. 'Jaggedness' of Cell-Free DNA Ends Correlates With Fetal, Tumor Origin, Study Finds Premium The method, called jagged end analysis by sequencing and developed by a team in Hong Kong, relies on DNA end repair with methylated or unmethylated cytosine. Prenetics, Prudential, CUHK, Others Partner to Increase COVID-19 Test Access in Hong Kong The Project Screen initiative aims to provide the Hong Kong community with home access to the World Health Organization-approved RT-PCR test for SARS-CoV-2 at zero profit to its organizers. Circular Cell-Free DNA in Plasma of Pregnant Women May Serve as Novel Biomarker A team led by researchers at the Chinese University of Hong Kong found that extrachromosomal circular DNA of fetal origin is smaller than that of maternal origin. Hong Kong's Take2 to Commercialize Early Cancer Detection Test; Focus on Healthcare Informatics Premium Take2 Health plans to launch an nasopharyngeal carcinoma early detection test in the next several months in Hong Kong and southern China. May 6, 2019 Hong Kong Startup Licenses Nasopharyngeal Cancer Early Detection Technology From Grail Oct 29, 2018 DNA Fragment End Analysis Could Improve Liquid Biopsy May 15, 2018 Team Describes Early Detection Test for Nasopharyngeal Carcinoma; Grail to Commercialize This Year Premium Aug 10, 2017 Cell-Free DNA Shows Promise for Nasopharyngeal Cancer Screening in Prospective Study May 31, 2017 Grail and Cirina Merge to Focus on Early Cancer Detection Dec 14, 2016 Noninvasive Prenatal Single-Gene Disease Testing to Benefit from Universal Method Premium Jun 16, 2016 Baylor, Chinese University of Hong Kong to Form Asian Center for Genetics Research Sep 21, 2015 Methylation Profiling of Cell-Free DNA Points to Tissue of Origin Premium Aug 25, 2015 CUHK Team Sequences Plasma DNA on MinIon, Demonstrating Feasibility of NIPT Premium Apr 29, 2014 Study Presents RNA Sequencing Approach for Profiling Fetal, Maternal Transcripts in Maternal Plasma Premium Oct 23, 2013 IP Watch: Hologic, Life Tech, Chinese U of Hong Kong, U of Toledo, IntegenX Win US Patents Premium Jul 31, 2013 Lo's Lab Publishes Non-invasive Prenatal Methylation Sequencing Method Premium May 8, 2013 IP Watch: UKMRC, Fujifilm, Life Techologies, 3M, Others Win US Patents Premium Oct 17, 2012 Lo Team Publishes Method for Whole-Genome Sequencing of Circulating Tumor DNA Premium Sep 13, 2012 Study Reveals Rice Genes Involved in Hybrid Sterility Jul 17, 2012 With Future of Roche NimbleGen Arrays in Question, Customers Bet on New Platforms Premium Jul 10, 2012 As More Labs Introduce Array-based Prenatal Dx Tests, Debate Rages over Indication, Platform Choice Premium May 30, 2012 Lo Team Finds Targeted, SNP-Based Approach for T21 Detection 'Less Robust' than Shotgun Sequencing Premium May 2, 2012 IP Watch: Cepheid, Illumina, DxNA, BioMerieux, Others Win US Patents Premium Aug 31, 2011 Quake Group Issued Patent for Detection of Fetal Aneuploidy with Next-Gen Sequencing Premium Load More Breaking News Pediatric Medulloblastoma Subgroups May Benefit from Lower-Dose Radiation Therapy Space Radiation Shows Limited Effects on Mammalian Sperm DNA, Fertility Bluestar Genomics Sues Former Consultant, Ludwig Institute for Cancer Research Over IP Ownership New Products Posted to GenomeWeb: 10x Genomics, Swift Biosciences, Agilent Technologies, More In Brief This Week: Quantum-Si, TGen, Yale, and More People in the News: New Appointments at Invitae, PGDx, Oxford Nanopore, PacBio, More The Scan Fertility Fraud Found Consumer genetic testing has uncovered cases of fertility fraud that are leading to lawsuits, according to USA Today. Ties Between Vigorous Exercise, ALS in Genetically At-Risk People Regular strenuous exercise could contribute to motor neuron disease development among those already at genetic risk, Sky News reports. Test Warning The Guardian writes that the US regulators have warned against using a rapid COVID-19 test that is a key part of mass testing in the UK. Science Papers Examine Feedback Mechanism Affecting Xist, Continuous Health Monitoring for Precision Medicine In Science this week: analysis of cis confinement of the X-inactive specific transcript, and more.