Chinese University of Hong Kong

Using Epstein-Barr virus DNA as a marker, investigators uncovered several individuals with early-stage nasopharyngeal cancers in a large screening effort in China.

Cirina will operate as a subsidiary of Grail and the combined entity will collaborate with Dennis Lo's lab at the Chinese University of Hong Kong. 

The approach, which uses 10x Genomics technology for haplotyping, requires neither mutation-specific assays nor DNA from affected family members.

The joint center will, among other things, design, establish, and conduct training in clinical genetics and genetic counseling tailored to key Asian regions.

Researchers used bisulfite sequencing to identify methylation markers in order to trace circulating DNA fragments back to their tissue of origin. 

The researchers sequenced plasma samples on the MinIon and found that NIPT could be feasible with improvements to accuracy, DNA extraction, and library prep.

NEW YORK (GenomeWeb) – A Chinese team led by Chinese University of Hong Kong researcher and Sequenom advisor Dennis Lo has demonstrated the feasibility of using RNA sequencing to profile fetal and maternal RNA transcripts in maternal blood.

Gen-Probe (Hologic) has been awarded US Patent No. 8,563,707, "Compositions and methods for detection of hepatitis A virus nucleic acid."
James Carlson and Steven Brentano are named as inventors.

Researchers from Dennis Lo's lab at The Chinese University of Hong Kong have adapted their non-invasive prenatal sequencing method for bisulfite sequencing to analyze the methylation status of fetal DNA in maternal plasma samples.

The UK's Medical Research Council has been awarded US Patent No. 8,435,775, "Mutant Pfu DNA polymerase."
Phillip Holliger, Nicola Ramsay, and Ann-Sofie Jemth are named as inventors.

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Mice in New York harbor both antibiotic-resistant bacteria and novel viruses, according to a new analysis of their fecal microbiomes.

Human Heredity and Health in Africa Initiative has issued guidelines for genomic research in the region, according to Nature News.

The Associated Press reports that an ethicist predicts that prenatal diagnosis and other advances will lead to more choices being available to prospective parents.

In Genome Biology this week: approach to analyze alternative polyadenylation, algorithm to predict transcriptomic structural variations, and more.