Chinese Academy of Sciences Human Population Nearly Went Extinct 900,000 Years Ago, Genetic Study Suggests Using genomic data from present-day humans and a new analytical approach, investigators found a population bottleneck that resulted in fewer than 1,300 breeding individuals. Chinese Multiomics Study Elucidates Aging Process in Women With data on more than 100 healthy women in China, researchers put together a set of aging clocks highlighting biological processes and potential biomarkers linked to aging. Consortium Produces Pangenome Reference Spanning Dozens of Chinese Populations Researchers put together a pangenome reference with high-quality, haplotype-phased genome assemblies for individuals from minority and majority populations in China. Qi Biodesign Bets on Agricultural Market With Genome Editing Technologies Premium The Chinese firm has developed a genome engineering tool to precisely insert large DNA fragments into plant genomes in order to develop desirable traits in crops. Mitochondrial Genome Analysis Points to Early Asian Migrations to the Americas, Japan Researchers retraced two historical migration events from northern China by focusing on a mitochondrial genome lineage called D4h and the sub-lineages that arose from it. May 9, 2023 Neanderthal DNA Left Mark on Shape of Some Human Noses, Genetic Study Finds Apr 24, 2023 Ankylosing Spondylitis Genomics Study Points to Genes, Pathways for Drug Discovery Mar 17, 2023 Tibetan Plateau Population Relationships, Adaptations Assessed With Ancient Genomes Mar 2, 2023 Grapevine Domesticated Simultaneously at Two Sites, Sequencing Study Finds Dec 30, 2022 Esophageal Cancer Molecular Study Highlights Tumor Subtypes, Treatment Response Markers Nov 23, 2022 Liver Cancers Detected With Parallel Mutation, Methylation Liquid Biopsy Approach Sep 23, 2022 Researchers Demonstrate Multiplex Codon Editing in the Human Genome Premium Jul 14, 2022 Analysis of Ancient DNA Reveals Ancestry of Mysterious Individual in Southwest China Apr 1, 2022 Study Finds Genetic Continuity Among Ancient Xinjiang Populations Alongside Influx From Other Groups Nov 17, 2021 Team Shares Chinese Genome Resource, Population Reference Panel Aug 25, 2021 Genetic Analyses Trace How Mutations Accumulate in Cells of the Human Body Over Time Oct 21, 2020 Gut Microbiome Analysis in Autistic Children Points to Detoxification Deficiencies Sep 4, 2020 Integrated Proteomic Study Leads to Metastasis, Response Clues in Chinese Colorectal Cancer Cases Aug 17, 2020 Single-Cell Transcriptomic Study Uncovers Cell Type That May Contribute to Prostate Cancer Jul 20, 2020 New CRISPR Base Editors Induce Targeted DNA Transversions Premium Jul 9, 2020 Integrated Proteomic Papers Define Lung Cancer Features Across Populations, Smoking Histories May 14, 2020 Historical East Asian Population Relationships, Migrations Proposed From Ancient Sequences Jan 31, 2020 Single-Cell Sequencing Study Suggests Antioxidant Pathway Role in Female Fertility Declines Aug 7, 2019 Spatial Transcriptome of Mouse Embryonic Development Drives Insight into Tissue Formation Jun 17, 2019 Risky Epstein-Barr Virus Variants Found in South China Nasopharyngeal Cancer Cases Load More Breaking News NanoString, A*Star, Next Level Genomics to Launch Spatial Biology Laboratory in Singapore FDA Approves Entrogen's RAS Mutation Detection Kit as CDx for Vectibix Cancer Predisposition Variants Increase Secondary Cancer Mortality Risk in Pediatric Survivors BostonGene, Johns Hopkins University Partner for Multiple Cancer Clinical Research Projects KromaTid, Noble Life Sciences Ink Distribution, OEM Agreement The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.