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Chinese Academy of Sciences

Gut Microbiome Analysis in Autistic Children Points to Detoxification Deficiencies

A quasi-paired cohort analysis identified shifts in the detoxifying function of gut microbes from individuals with autism spectrum disorder.

Integrated Proteomic Study Leads to Metastasis, Response Clues in Chinese Colorectal Cancer Cases

Using proteomic, phosphoproteomic, and genomic data, researchers uncovered informative features in primary and metastatic samples from almost 150 CRC cases in China.

Single-Cell Transcriptomic Study Uncovers Cell Type That May Contribute to Prostate Cancer

Single-cell analysis identified different clusters of luminal cells in the prostate, one of which may contribute to the development of prostate cancer.

New CRISPR Base Editors Induce Targeted DNA Transversions
Premium

The technology could be developed into therapies for diseases caused by DNA transversion point 

Integrated Proteomic Papers Define Lung Cancer Features Across Populations, Smoking Histories

Three research teams profiled proteomic, genomic, and other features in lung adenocarcinomas in Asia and other parts of the world, including cases in never-smokers.

May 14, 2020

Historical East Asian Population Relationships, Migrations Proposed From Ancient Sequences

Jan 31, 2020

Single-Cell Sequencing Study Suggests Antioxidant Pathway Role in Female Fertility Declines

Aug 7, 2019

Spatial Transcriptome of Mouse Embryonic Development Drives Insight into Tissue Formation

Jun 17, 2019

Risky Epstein-Barr Virus Variants Found in South China Nasopharyngeal Cancer Cases

Feb 8, 2019

Schizophrenia Regulatory Mechanisms Revealed by Risk SNP Functional Analysis

Jan 16, 2019

Population Size May Enable Cancer Cell to Avoid Mutational Meltdown

Jan 10, 2019

Leukemia Study Finds DNA Methylation Differences Between Male, Female CLL Patients

Aug 1, 2018

Two Research Teams Engineer Yeast With Fewer Chromosomes Than Typical

May 7, 2018

Cotton Resequencing Studies Lead to New Trait Associations, Domestication Insights

Apr 25, 2018

3,000 Rice Genomes Project Sequences Reveal Asian Rice History, Diversity

Mar 20, 2018

Cockroach Genome Harbors Gene Expansions That Could Help it Adapt to Urban Environments

Jan 29, 2018

Esophageal Cancer GWAS Leads to Low-Frequency Risk Variants

Nov 30, 2017

Human SARS Virus Found Piecemeal in Different Bat Coronaviruses From One Cave

Oct 12, 2017

Sea Cucumber Genome Imparts Insight on Genes Linked to Organ Regeneration

Sep 13, 2017

Orchid Features, Evolutionary History Informed by New Genome Sequence

May 1, 2017

Tea Tree Genome Provides Insight on Flavor, Caffeine Production

Mar 3, 2017

Northern Snakehead Fish Genome Sequenced

Jan 26, 2017

Genetic Variants Affect Tomato Flavor Through Sugar Production, Other Pathways

Nov 8, 2016

Peach GWAS Leads to Loci Linked to Fruit Traits

Jun 10, 2016

Refined Deep Sequencing Technique Enables Profiling of Small RNAs in Mouse Embryos

Breaking News
The Scan

Another Resignation

According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug.

Novavax Finds Its Vaccine Effective

Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19.

Can't Be Used

The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports.

PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More

In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.