Chinese Academy of Sciences Gut Microbiome Analysis in Autistic Children Points to Detoxification Deficiencies A quasi-paired cohort analysis identified shifts in the detoxifying function of gut microbes from individuals with autism spectrum disorder. Integrated Proteomic Study Leads to Metastasis, Response Clues in Chinese Colorectal Cancer Cases Using proteomic, phosphoproteomic, and genomic data, researchers uncovered informative features in primary and metastatic samples from almost 150 CRC cases in China. Single-Cell Transcriptomic Study Uncovers Cell Type That May Contribute to Prostate Cancer Single-cell analysis identified different clusters of luminal cells in the prostate, one of which may contribute to the development of prostate cancer. New CRISPR Base Editors Induce Targeted DNA Transversions Premium The technology could be developed into therapies for diseases caused by DNA transversion point Integrated Proteomic Papers Define Lung Cancer Features Across Populations, Smoking Histories Three research teams profiled proteomic, genomic, and other features in lung adenocarcinomas in Asia and other parts of the world, including cases in never-smokers. May 14, 2020 Historical East Asian Population Relationships, Migrations Proposed From Ancient Sequences Jan 31, 2020 Single-Cell Sequencing Study Suggests Antioxidant Pathway Role in Female Fertility Declines Aug 7, 2019 Spatial Transcriptome of Mouse Embryonic Development Drives Insight into Tissue Formation Jun 17, 2019 Risky Epstein-Barr Virus Variants Found in South China Nasopharyngeal Cancer Cases Feb 8, 2019 Schizophrenia Regulatory Mechanisms Revealed by Risk SNP Functional Analysis Jan 16, 2019 Population Size May Enable Cancer Cell to Avoid Mutational Meltdown Jan 10, 2019 Leukemia Study Finds DNA Methylation Differences Between Male, Female CLL Patients Aug 1, 2018 Two Research Teams Engineer Yeast With Fewer Chromosomes Than Typical May 7, 2018 Cotton Resequencing Studies Lead to New Trait Associations, Domestication Insights Apr 25, 2018 3,000 Rice Genomes Project Sequences Reveal Asian Rice History, Diversity Mar 20, 2018 Cockroach Genome Harbors Gene Expansions That Could Help it Adapt to Urban Environments Jan 29, 2018 Esophageal Cancer GWAS Leads to Low-Frequency Risk Variants Nov 30, 2017 Human SARS Virus Found Piecemeal in Different Bat Coronaviruses From One Cave Oct 12, 2017 Sea Cucumber Genome Imparts Insight on Genes Linked to Organ Regeneration Sep 13, 2017 Orchid Features, Evolutionary History Informed by New Genome Sequence May 1, 2017 Tea Tree Genome Provides Insight on Flavor, Caffeine Production Mar 3, 2017 Northern Snakehead Fish Genome Sequenced Jan 26, 2017 Genetic Variants Affect Tomato Flavor Through Sugar Production, Other Pathways Nov 8, 2016 Peach GWAS Leads to Loci Linked to Fruit Traits Jun 10, 2016 Refined Deep Sequencing Technique Enables Profiling of Small RNAs in Mouse Embryos Load More Breaking News Alzheimer's Disease Phosphoproteomics Study Uncovers Signaling Abnormalities Genetic Analysis of H. Pylori Indicates Americas Colonized in One Main Migration Event BillionToOne Raises $55M in Series B Financing GeninCode to Launch Cardiovascular Disease Risk Tests in US With Eversana Top Five Articles on GenomeWeb Last Week: Illumina, Liquid Biopsy, Thermo Fisher Scientific, and More Becton Dickinson Sues Beckman Coulter Over Cell Analysis, Sorting IP The Scan Another Resignation According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug. Novavax Finds Its Vaccine Effective Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19. Can't Be Used The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports. PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.