Chinese Academy of Sciences

In Nucleic Acids Research this week: collection of epigenome-wide association study data, updated BloodSpot database, and more.

In Genome Research this week: transcriptomic profiles of centenarians, role for PRDM9 expression in various tumor types, and more.

Researchers in China have generated mouse pups from same-sex parents, according to Scientific American.

In Genome Biology this week: DNA methylation in soybean accessions, genetic ancestry of Uralic speakers, and more.

In Genome Research this week: queen bee chromatin profiles, quantitative trait loci and allele-specific expression in wild house mice, and more.

Scientific American writes that shifting the balance of GRF4-DELLA in rice could lead the crop to use nitrogen more efficiently.

One Base

Wired reports that researchers in China have used base editing to fix a Marfan syndrome-linked mutation in human embryos.

The teams, from the Chinese Academy of Sciences and NYU Langone Health, generated viable yeast strains with just one or two chromosomes.

Researchers identified trait-related variants by sequencing more than 400 upland cotton accessions and nearly 250 representatives from two diploid Gossypium species.

Based on genome data for 3,010 Asian rice accessions, researchers retraced the domestication history and diversity of Xian/Indica and Geng/Japonica rice.

Pages

Publication of He Jiankui's work on gene-edited infants would raise ethical concerns for journals, Wired and others report.

The New York Times reports that evidence linking trauma in one generation to epigenetic effects that influence subsequent generations may be overstated.

ScienceInsider reports that US National Institutes of Health researchers were told in the fall they could not obtain new human fetal tissue.

In PNAS this week: skin pigmentation evolution among KhoeSan, biomarkers for dengue virus progression, and more.