Children's Hospital Los Angeles

Children's Hospital Los Angeles has agreed to implement Edico Genome's Dragen Bio-IT suite, including the somatic and RNA seq pipelines.

Researchers have been able to detect and characterize genomic alterations in DNA floating in the aqueous humor of the eye, opening the door to new prognostic studies.

The lab-developed test will use Thermo Fisher Scientific's Ion sequencing platform and will be applicable to most childhood cancers. 

The consortium is composed of six children's hospitals including Children's Hospital Los Angeles; Rady Children's Hospital, San Diego; and Children's Hospital Colorado.

The new gene panel is based on DNA and RNA sequencing research and will utilize Thermo's Ion Torrent platform and Ion AmpliSeq technology.

The new investment will go towards the areas of cancer, inherited diseases, and infectious diseases, with an initial focus on pediatric cancer.

WaferGen Biosystems and collaborators in the laboratory of Jo Vandesompele at the University of Ghent have developed a PCR-based target enrichment workflow using WaferGen's SmartChip real-time PCR system, the company said this week.

The group expects delivery of two Ion PGMs by the end of the month, and will use them for "targeted, clinically relevant studies," said Timothy Triche, director of the center for personalized medicine at Children's Hospital Los Angeles.

Timothy Triche will use the award to establish a next-generation sequencing core facility to study high-risk childhood cancer.

Researchers test gene therapy targeting a different cancer protein in a new trial, the New York Times reports.

Pennsylvania State University researchers found that salivary microRNAs could predict which kids would have longer concussion symptoms, according to NPR.

The Associated Press reports Alex Azar, the new Department of Health and Human Services secretary nominee, made millions of dollars as a pharmaceutical executive.

In PNAS this week: immune profiling of breast cancer, transposable element patterns in rice, and more.