Case Western Reserve University

This Week in PNAS

In PNAS this week: computational approach combining cancer survival models and machine learning, auxin herbicide resistance mutation, and more.

Working with Case Western Reserve University, the firm will sequence fecal samples from individuals diagnosed with autism and provide results for free to the research community.  

The five-year award will provide funding for researchers to investigate genetic determinants of Barrett's Esophagus and esophageal adenocarcinoma.

The assay analyzes a digital image of tumor tissue sample to identify ER-positive breast cancer patients who are candidates for adjuvant chemotherapy.

The method detects somatic copy number alterations in whole-exome datasets without requiring input from users and irrespective of sequencing platform. 

The tests will use PGT's VeriTag technology in order to detect drug-resistant mutations at the .1 percent level. 

University Hospitals' Deepgen HIV assay will use Advanced Biological Laboratories' DeepChek software to help monitor drug resistance and minority variants in HIV strains. 

Four projects have received funding from the NIH, including a proteomics-directed study targeting Mycobacterium tuberculosis and an NCI multi-site prospective study of glioma patients.


360Dx reports that the US Centers for Medicare & Medicaid Services would cover next-generation sequencing-based cancer panel tests.

The Washington Post reports that a meteorologist is being considered as presidential science and technology advisor.

In PNAS this week: precision medicine strategy to screen for disease risk, genome evolution in Haemophilus influenzae, and more.

Researchers have developed a PCR-based assay to gauge whether manatees are present in waters.