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Carnegie Mellon

NIH Kicks Off Second Stage of 4D Nucleome Program With $142M in Research Grants

The first stage generated a range of tools and resources for studying the nucleus in time and space including publicly available datasets and software.

Pittsburgh Supercomputing Center, Indiana U Win $1.3M in NSF Funding for Genomics Program

With the three-year grants, the institutions will continue an initiative that is developing tools and technologies for genome biology research.

Yale-Led Gene Editing Study Uses PNAs to Correct Hemoglobin Gene in Human CD34 Cells, Mice
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The researchers reported correcting beta thalassemia in a mouse model via a gene editing method delivered by an intravenous injection.

Q&A: Carnegie Mellon's Robert Murphy Discusses Goals, Benefits of New Computational Biology Degree
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The curriculum will cover computer science and experimental biology courses and offer opportunities for students to contribute to faculty research projects.

New Algorithm Simultaneously Identifies Structural Variants, Copy Number Changes in Cancer Genomes
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The method quantifies structural variations in an allele-specific manner, providing an integrative way to study complex SVs and copy number alterations. 

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The Scan

Genes Linked to White-Tailed Jackrabbits' Winter Coat Color Change

Climate change, the researchers noted in Science, may lead to camouflage mismatch and increase predation of white-tailed jackrabbits.

Adenine Base Editor Targets SCID Mutation in New Study

Researchers from the University of California, Los Angeles, report in Cell that adenine base editing was able to produce functional T lymphocytes in a model of severe combined immune deficiency.

Researchers Find Gene Affecting Alkaline Sensitivity in Plants

Researchers from the Chinese Academy of Science have found a locus affecting alkaline-salinity sensitivity, which could aid in efforts to improve crop productivity, as they report in Science.

International Team Proposes Checklist for Returning Genomic Research Results

Researchers in the European Journal of Human Genetics present a checklist to guide the return of genomic research results to study participants.