Cardiff University
Schizophrenia Study Implicates Ultrarare Variants in Cognitive Features
With exome sequence data for more than 800 cognitively profiled schizophrenia patients, investigators saw an overrepresentation of ultrarare coding variants in reduced cognition cases.
Schizophrenia, Bipolar Disorder Risk Traced to Common, Rare Variants in New Genetic Studies
Researchers found that rare and common genetic risk factors for schizophrenia discovered in the two studies converged on many of the same biological mechanisms.
Genetic Links Between Psychotic Experiences, Neuropsychiatric Diseases Uncovered in Study
Researchers also uncovered associations between any psychotic experience and the genetic liability for schizophrenia, major depressive disorder, and bipolar disorder.
Lynch Syndrome Mutation Study Suggests Changes to Clinical Management
Investigators pooled older and new data from the Prospective Lynch Syndrome Database, tracking outcomes for different mutations across age and gender groups.
Schizophrenia Genes, Pathways in Brain Identified With Transcriptome Imputation Approach
With available brain data, researchers came up with expression prediction models for finding new schizophrenia-related genes in a larger case-control set.