CalTech ENCODE Phase Three Offers New Insights Into Genomic Regulatory Regions, Organization In more than a dozen new papers, ENCODE researchers reported on analyses of the human and mouse genomes, using new data types and additional tissues. Chan Zuckerberg Initiative Awards $3.8M in Grants for Open-Source Biomedical Software Projects The funding marks the second cycle of CZI's Essential Open Source Software program, which awards between $50,000 and $250,000 in total costs per project. New Method Captures Higher-Order Chromatin Contacts With Nanopore Sequencing Premium Unlike the Hi-C chromosome conformation assay, the Pore-C technique reveals information that's lost with short-read sequencing. 'Digital' Nucleic Acid Amplification Shows Promise for Rapid Antibiotic Susceptibility Testing Premium A new assay uses digital loop-mediated isothermal amplification (dLAMP) to perform phenotypic antibacterial susceptibility testing in 30 minutes. NIH Awards Gene Ontology Consortium $2.7M to Improve Knowledgebase The funding will be used to develop new software and data structures to enable researchers to use the GO data for network-based analysis. Feb 3, 2017 NHGRI Commits $31.5M to Expand ENCODE Project Oct 27, 2015 JPL Researchers Characterize International Space Station Microbiome Oct 28, 2014 IP Roundup: CalTech, QuantumDx, Fluidigm Win US Patents Premium Dec 5, 2013 Using $15M DARPA Award, Caltech Team Shows Robust Digital Isothermal PCR on 'SlipChip' Device Premium Dec 3, 2013 IP Roundup: Fluidigm, Affymetrix, Illumina, CalTech, IBM, CapitalBio, Tsinghua University, and Others Premium Oct 15, 2013 IP Roundup: CalTech, Maven Technologies, Cancer Genetics, Fujifilm, Enzo Life Sciences Premium Aug 29, 2013 Teams Scour Parasitic Worm Genome, Transcriptomes for Signs of Vulnerability Jul 30, 2013 IP Watch: CalTech, Synthetic Genomics, Life Tech, LLNL, Others Win US Patents Premium Jul 17, 2013 IP Watch: CalTech, Ambergen, Enzo, Qiagen, Life Tech Among Recent US Patent Winners Premium Jun 4, 2013 IP Roundup: Optomec, CalTech, Intelligent Bio-Systems, Arborgen Premium Feb 26, 2013 IP Roundup: Caltech, U of California, Rheonix, Roche NimbleGen, Silicon Biosystems, and More Premium Oct 24, 2012 CTAF Recommends Sequencing-Based Screening Tests for T21 and T18 in High-Risk Women Premium Sep 25, 2012 IP Roundup: Affymetrix, Scienion, Bio-Layer, Canon, Samsung, Cal Tech Premium Sep 4, 2012 IP Roundup: Regeneron, CalTech, X-Body, Cell ASIC, Corning, UT Austin, Affymetrix, Lumencor Premium Aug 2, 2012 IP Watch: Canon, Caltech, Bio-Rad, LLNL, DuPont, and Arkray Win US Patents Premium May 24, 2012 DARPA Awards $15.6M for Synthetic Biology Machinery, Methods Mar 6, 2012 IP Update: California Institute of Technology; Roche NimbleGen; Corning; and More Premium Feb 28, 2012 IP Update: California Institute of Technology; Progenika Biopharma; National Livestock Breeding Center; and More Premium Jan 31, 2012 IP Update: California Institute of Technology; Fluidigm; Life Technologies; and More Premium Nov 1, 2011 IP Watch: Takara Bio, Abbott, Gen-Probe, CalTech, U of Utah, Penn State, and Duke Win US Patents Premium Load More Breaking News Dilated Cardiomyopathy Gene Mutations Point to Possible Therapeutic Strategy Ginkgo Bioworks Acquires Massachusetts COVID-19 Testing Firm Mainz Biomed Taps DCN Dx to Aid European Study of Enhanced ColoAlert Assay Parse Biosciences Partners With Research Instruments for Southeast Asia Distribution Thermo Fisher, Oncocyte Ink Development, Comarketing Deal for Cancer IVDs Yourgene Health Enters Three-Year £5M Term Loan Facility The Scan And a Fourth? A fourth dose of the Pfizer-BioNTech SARS-CoV-2 vaccine in an Israeli study increased antibody levels but did not prevent Omicron variant infections, according to the Financial Times. For Better Science Software A virtual institute funded by former Google CEO Eric Schmidt's philanthropy aims to lure software engineers to academia, Science reports. Recommendation Explanations The New York Times writes that the US Centers for Disease Control and Prevention is straining to both make and explain decisions based on limited information. Genome Research Papers on De Novo Mutation Rates, Polyploid Genotyping, Oncogene Epigenomic Translocation In Genome Research this week: de novo mutations rates in hemoglobin subunits, analysis of variant calling methods for polyploid plants, and more.