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Broad Institute

Researchers developed a system for continuous evolution of base editors, which should continue to improve their functionality.

The Broad will now offer licenses for both its own CRISPR IP and MilliporeSigma's to companies using CRISPR in their research and development activities.

Researchers tracked down monogenic risk variants, carriers, disease culprits, and more for 50 individuals with cardiomyopathy and 50 unaffected participants.

The US Patent and Trademark Office is opening another interference proceeding in the CRISPR patent fight.

The process challenges claims made in certain UC Berkeley patents on the use of CRISPR-Cas9 to edit eukaryotic genomes.

Broad Institute researchers describe an approach they've dubbed "DNA microscopy."

So-called DNA microscopy is the latest entrant to the rapidly growing spatial genomics field that combines molecular analysis with imaging.

A small but significant proportion of autism spectrum disorder cases — particularly those occurring in females — appeared to involve biallelic loss-of function or missense mutations.

Researchers from the Broad Institute and NIH characterized a CRISPR-associated transposase that can integrate DNA into unique sites in the E. coli genome.

Most individuals had at least one tissue, of the 29 studied, containing clonal mutations, some of which are typically found in cancer cells.

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A Minnesota toddler given a gene therapy to treat her spinal muscular atrophy is now walking, according to Newsweek.

NBC Bay Area reports a California lab has been certified to conduct forensic mitochondrial DNA sequencing.

The New York Times reports on how environmental DNA sampling could monitor endangered species.

In Cell this week: proteomic, genomic, and transcriptomic analysis of endometrial cancer; deep neural network learning-based approach to antibiotic discovery; and more.