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Broad Institute

Two new grants are helping the company develop its SHERLOCK and INSPECTR technologies as the basis for creating innovative diagnostics.

The prime editing technique has strengths that are complementary to nuclease-based editing and base editing.

A study presented at ASHG Tuesday showed that newly identified schizophrenia risk genes appear to have some overlap with genes involved in autism spectrum disorder.

The system uses the Cas13 nuclease to identify target sites in various RNA viruses and then destroy them.

In Genome Research this week: new tool to identify protein coding sequences, droplet digital PCR-based assay to quantify mitochondrial DNA, and more.

The partners will codevelop software for both small and large variant detection and Illumina will create hardware-accelerated versions for its Dragen platform.

The Broad Institute spinout will develop its CRISPR-based Sherlock platform for battlefield-ready diagnostics for infectious disease agents.

Using 350 human genomes from different populations, the two centers plan to develop a multi-genome reference sequence that is as complete as possible.

The researchers believe that combining liquid and tissue biopsy can improve diagnostic and therapeutic options for cancer patients with acquired drug resistance mutations.

A study published this week describing the new approach shows higher resolution than an earlier method that 10x Genomics is commercializing.

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The Centers for Disease Control and Prevention estimates more people get sick and die from drug-resistant germs than previously thought, the Washington Post reports.

According to the Associated Press, three universities and a healthcare institution are sharing a gift of $1 billion.

New rules seek to limit the type of scientific and medical research that can be used to guide public health regulations, the New York Times reports.

In Nature this week: FreeHi-C approach simulates Hi-C data from interacting genome fragments, and more.