Broad Institute

Edge of Nonprofit

At Stat News, Jim Kozubek argues that the Broad Institute is pushing the boundary of what a nonprofit is.

 The researchers noted that heritability of PTSD differed by sex, and that it overlapped with schizophrenia and other mental disorders. 

These cell subtypes could help researchers gain a clearer understanding of cell mechanics and find better targets for potential therapies.

Incorporating splicing and other clues from muscle transcripts, researchers reached diagnoses in cases that were inconclusive after sequencing alone.

A pair of studies also uncovered atrial fibrillation risk loci specific to East Asian populations, particularly near SH3PXD2A.

This Week in Science

In Science this week: CRISPR-based approach to diagnose disease, new whole-genome amplification approach, and more.

Dubbed "Sherlock," the new technology has demonstrated potential in detecting viruses and bacteria as well as human SNPs and mutations in cell-free DNA.

The University of California is appealing the recent CRISPR/Cas9 patent decision.

Reinstating the CRISPR patent interference with the Broad Institute would allow UC to argue that Jennifer Doudna and Emmanuelle Charpentier invented it first.

Protein patterns in patient-derived xenografts sometimes pointed to different alterations than those predicted from somatic mutation and expression data.

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A fire at a Manchester hospital may have destroyed lab equipment and data, the Guardian reports.

Researchers generate a genetic database from skeletal remains from the 1845 Franklin Expedition to the Arctic, Live Science reports.

Researchers in China have begun another trial using CRISPR/Cas9 approaches in cancer patients, according to the Wall Street Journal.

In Science this week: human DNA found in sediments from archeological sites lacking bones, and more.