Broad Institute
In Brief This Week: MDxHealth, Agilent Technologies, IsoPlexis, IntegraGen, More
News items for the week of Jan. 9, 2023.
Study Traces Maternal Impacts on Developing Infant Gut Microbe, Metabolite Features
Researchers identified horizontal gene transfer between maternal and infant microbiomes, as well as other factors contributing to infant gut microbiome development.
Computational Tool Tracks Genetic Variation Effects of Off-Target Gene Editing
Researchers came up with a strategy for predicting off-target edits related to genetic variation, using it to assess off-target variant effects on a potentially therapeutic guide RNA.
Ashkenazi Jewish Population History Revealed With Ancient DNA Analysis
Along with evidence of an earlier founder event, samples from a 14th century German cemetery revealed ties between ancient and modern-day Ashkenazi Jewish populations.
Complex Trait-Related CNVs Unearthed Using Haplotype-Informed Approach
Researchers tracked down 269 associations between complex traits and copy number variants uncovered with the help of haplotype-informed copy number variation analyses.