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The researchers believe that combining liquid and tissue biopsy can improve diagnostic and therapeutic options for cancer patients with acquired drug resistance mutations.

A study published this week describing the new approach shows higher resolution than an earlier method that 10x Genomics is commercializing.

By sequencing an Indus Valley Civilization representative and related individuals, investigators learned more about the South Asian ancestry, farming history, and languages.

Researchers identified five loci that were overrepresented in individuals with past, self-reported same-sex sexual behavior, though the associations were complex.

The NAM, NAS, and Royal Society have formed a commission to develop a framework on the proper use of genome editing, and convened its first meeting in Washington, DC, this week.

Investigators saw signs that risky TP53 missense mutations may interfere with wild type copies of the tumor suppressor gene in acute myeloid leukemia and other myeloid cancers.

The Broad Institute called UC's new legal strategy "deeply unfortunate" and called on the university to "move beyond litigation."

As MPEG LA tries to complete its larger CRISPR IP patent pool, smaller license agreements continue and a mini-pool has emerged between key players.

Using single-cell RNA-seq and other approaches, researchers looked at the four known medulloblastoma subtypes and the brain cell types from which they arise.

Researchers developed a system for continuous evolution of base editors, which should continue to improve their functionality.

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NPR says the explosion and fire earlier this week at a Russian lab that stores dangerous pathogens revives the question of whether such samples should be kept.

According to Wired, Nebula Genomics is providing a way for people to get their genomes sequenced anonymously.

A 26-year-old woman tells Cosmopolitan about learning her APOE status at a young age.

In Science journals this week: a functional genomic screen uncovers drug combination that increases KRAS inhibitor efficacy in aggressive lung cancer, and more.