The clinic will offer comprehensive DNA sequencing, interpretation, and reporting of disease-associated genes for healthy adults and their children.
Investigators saw signs that risky TP53 missense mutations may interfere with wild type copies of the tumor suppressor gene in acute myeloid leukemia and other myeloid cancers.
The grant recipients will receive up to $5 million each and are led by scientists at institutions including Harvard Medical School and the Cleveland Clinic.
Researchers tracked down monogenic risk variants, carriers, disease culprits, and more for 50 individuals with cardiomyopathy and 50 unaffected participants.
Researchers at Harvard, Peking University, and Yikon Genomics suggested that their noninvasive test is more specific than the prevailing biopsy-based method.
Harvard and Brigham and Women's Hospital researchers will help guide Sanford in using and interpreting data collected through its Sanford Chip pharmacogenomic test.
A pair of new studies evaluated the effectiveness of cytologic and HPV-based testing approaches at varied screening intervals for identifying women at risk of cervical cancer.
As CRISPR technology continues to progress, some researchers are turning their focus to discovering or developing countermeasures and controls.
Researchers used the platform to identify small synthetic molecules that disrupt the editing activity of the SpCas9 nuclease.
Early-access users of the Flongle said the small, inexpensive flow cells allow them to develop new methods quickly and to check the quality of clones and libraries.
The Wall Street Journal looks into FamilyTreeDNA's handling of genetic genealogy searches by law enforcement.
In a point-counterpoint in the Boston Globe, researchers discuss the potential of gene editing to prevent Lyme disease, but also the pitfalls of doing so.
MIT's Technology Review reports that researchers hope to develop a CRISPR-based pain therapy.
In Science this week: atlas of malaria parasites' gene expression across their life cycles, and more.