Brigham and Women's Hospital Parkinson's Disease Progression Linked to Five Variants in Genome-Wide Survival Study The researchers also developed a polygenic hazard score to predict which individuals with Parkinson's are likely to develop disease-related dementia. Renal Cell Carcinoma Risk Gene Representation Can Vary With Ancestry While risky variants in the FH gene were more common in renal cell carcinoma patients with African ancestry, European patients more often carried pathogenic CHEK2 gene changes. Dana Farber Team Applies PCR Method to ID Microsatellite Instability in Tumor-Derived Samples Premium The group aims to adapt the method, which detects poly-adenine tails, to monitor for minimal residual disease in late-stage colon cancer patients after surgery. Disease-Linked Mutations May Affect Protein-Protein Interactions, Influence Drug Response Both germline variants and somatic tumor variants linked to disease are more likely to disrupt protein-protein interactions than other variants. Genetic Risk of Cognitive Decline Varies Between Latino Populations, Study Finds The APOE-ε4 allele, a major genetic risk factor for Alzheimer's disease, conveys more risk among Cuban than other Latino populations, the analysis found. Oct 16, 2020 Disparity in Microsatellite Instability Testing Suggests Need to Close Socioeconomic Access Gaps Premium Jun 30, 2020 Fluxergy, Mass General Brigham Partner to Evaluate Rapid COVID-19 Molecular Testing System Jun 23, 2020 Tissue Network Analysis Points to Significant Sex-Related Regulatory Differences Jun 22, 2020 Stanford Spinout Levitas Bio to Launch Magnetic Levitation Cell Separation Platform Premium May 11, 2020 Quanterix Licenses Multiplex SARS-CoV-2 Serology Test From Brigham and Women's Apr 16, 2020 Biogen Launches Employee COVID-19 Biobank With Broad Institute, Partners HealthCare Mar 16, 2020 Mass General, Brigham and Women's Open Clinics to Integrate Genomics Into Primary Care Premium Feb 12, 2020 Monogenic Hypercholesterolemia Increases Cardiovascular Disease Risk More Than Polygenic Form Dec 6, 2019 Cancer Susceptibility Contributions of Non-Coding SNPs Clarified With Network Approach Oct 31, 2019 Chromosomal Abnormalities Associated With Recurrent Miscarriage Emerge from Sequencing Study Aug 16, 2019 Brigham and Women's Hospital Opens Preventive Genomics Clinic Aug 8, 2019 Dominant-Negative Effect Detected for Missense TP53 Mutations in Myeloid Cancers Jul 24, 2019 Gray Foundation Awards $25M in Cancer Research Grants Jun 27, 2019 MedSeq Team Reports Genome Analysis, Reanalysis Results for 100 Participants Jun 27, 2019 Noninvasive Preimplantation Aneuploidy DNA Test Shows Promise But Concerns Remain Premium Jun 13, 2019 Sanford Health Taps Harvard, Brigham and Women's for Genetic Screening Study May 13, 2019 Studies Outline Outcomes Associated With Cervical Cancer Screening, Triage Strategies May 8, 2019 Anti-CRISPR Proteins, Molecules Present Tantalizing Options for Control of Therapies, Gene Drives Premium May 2, 2019 Anti-CRISPR Small Molecule Discovered Using New High-Throughput Screening Platform Mar 18, 2019 Nanopore Sequencing Adapter Enables Low-Cost Experiments, May Broaden Technology's Use Premium Load More Breaking News Alzheimer's Disease Phosphoproteomics Study Uncovers Signaling Abnormalities Genetic Analysis of H. Pylori Indicates Americas Colonized in One Main Migration Event BillionToOne Raises $55M in Series B Financing GeninCode to Launch Cardiovascular Disease Risk Tests in US With Eversana Top Five Articles on GenomeWeb Last Week: Illumina, Liquid Biopsy, Thermo Fisher Scientific, and More Becton Dickinson Sues Beckman Coulter Over Cell Analysis, Sorting IP The Scan Another Resignation According to the Wall Street Journal, a third advisory panel member has resigned following the US Food and Drug Administration's approval of an Alzheimer's disease drug. Novavax Finds Its Vaccine Effective Reuters reports Novavax's SARS-CoV-2 vaccine is more than 90 percent effective in preventing COVID-19. Can't Be Used The US Food and Drug Administration says millions of vaccine doses made at an embattled manufacturing facility cannot be used, the New York Times reports. PLOS Papers on Frozen Shoulder GWAS, Epstein-Barr Effects on Immune Cell Epigenetics, More In PLOS this week: genome-wide association study of frozen shoulder, epigenetic patterns of Epstein-Barr-infected B lymphocyte cells, and more.