In Nature this week: genetic and proteomic data gives Alzheimer's disease development insights, whole-genome doubling could be targeted in cancer, and more.
In Genome Research this week: approach to predict gene expression from single-cell DNA methylation profiles, oral microbiome of children with cavities, and more.
Using exome data from Alzheimer's disease cases and controls with or without the APOE4 risk allele, investigators identified potential risk-stratifying variants.
Cancer Moonshot-funded teams are profiling pre-cancers in an effort to establish targeted treatment, detection, and prevention methods that can be applied before cancers form.
Conducting studies on Latina and African-American women produces population-specific insights on the genetics of the disease that aren't possible to glean in European-heavy GWAS.
The company is hoping that consumers will use its platform to manage their health data, to participate in research, and to learn about their own and their family's health risks.