In Genome Biology this week: genomic sequencing of milkweed bug, benchmark comparison of single-cell RNA sequencing platforms, and more.
In the hunt for an antigen in solid tumors that CAR-T cells can target, researchers demonstrate the safety and efficacy profile of two such agents in early studies.
In Cell this week: somatic mtDNA mutation-based "genetic barcode" method, molecular mechanisms behind structural variants at 17p11.2, and more.
The Personal Genome Sequencing Outcomes (PeopleSeq) Consortium surveyed more than 500 early adopters who underwent personal genome or exome sequencing.
In a clinical study Baylor researchers found that PreSeek, which Natera markets as Vistara, reliably detected dominant disorders in more than 400 pregnancies.
At the PAG conference, researchers said they are sequencing 100 tomato genomes in 100 days using Oxford Nanopore's PromethIon and a pipeline for maximizing SV diversity.
In PLOS this week: somatic mutation associations unearthed in thousands of cancer exomes, pathogen detection assay, and more.
Each stage is associated with an increase in gut microbial diversity and is influenced by breastfeeding, researchers reported this week.
The centers will generate genomic data from biosamples contributed by participants in the program and analyze data that will be returned to them.
Using Cancer Genome Atlas data, the researchers identified about 1,100 genes in a range of cancer types whose expression is disrupted by structural variants.
Bloomberg reports that the DNA-for-cash deal reported in Kentucky might be a more widespread scam.
St. Jude Children's Research Hospital scientists have treated infants with X-linked severe combined immunodeficiency using gene therapy in an early phase study.
St. Louis Public Radio reports that some African Americans are turning to DNA ancestry testing to help guide genealogical searches.
In Nature this week: a genomic analysis of the snailfish Pseudoliparis swirei, ancient DNA analysis gives insight into the introduction of farming to England, and more.