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Babraham Institute

Enhanc3D Genomics Launches With £10M in Funding to Support 3D Genome Mapping Software
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Babraham Institute spinout Enhanc3D Genomics is offering a software platform to provide high-resolution 3D mapping of noncoding regions of the human genome.

Catalog of Promoter Interactions Links Non-Coding Variants, Gene Promoters

Babraham Institute researchers used promoter capture Hi-C to determine the interactomes of 31,000 promoters in blood cells.

UK Team Combines Methylation, Transcriptome Sequencing in Single Cells
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In a paper published today in Nature Methods, the researchers applied scM&T-seq to profile the transcriptomes and epigenomes of mouse embryonic stem cells.

Babraham Institute-led Team Debuts Single-cell Bisulfite Sequencing Method
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NEW YORK (GenomeWeb) – A UK research team has come up with a new method for applying bisulfite sequencing-based methylation profiling to individual cells.

Babraham Institute to Use DNAStar's Lasergene for Sequence Assembly, Analysis
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DNAStar said this week that researchers at the Babraham Institute will use its Lasergene software for sequence assembly and analysis. The financial terms of the licensing arrangement were not disclosed.
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The Scan

Open Pediatric Brain Tumor Atlas Team Introduces Genomic Data Collection, Analytical Tools

A study in Cell Genomics outlines open-source methods being used to analyze and translate whole-genome, exome, and RNA sequence data from the Pediatric Brain Tumor Atlas.

Neurological Outcomes Linked to Innate Immune Features After Cardiac Arrest

Researchers reporting in Med dig into immune features found a few hours after cardiac arrest that correspond with neurological outcomes.

Mouse Study Finds Circadian Rhythm-Related Gene Expression Changes Linked to Sleep Apnea

A paper in PLOS Biology reveals tissue-specific circadian rhythm and gene expression patterns in an intermittent hypoxia-based mouse model of obstructive sleep apnea.

Polygenic Risk Score to Predict Preeclampsia, Gestational Hypertension in Pregnant Women

Researchers in Nature Medicine provide new mechanistic insights into the development of hypertensive disorders of pregnancy, which may help develop therapeutics.