In a cohort of more than 150 patients, none who responded well to anti-androgen therapy had AR-V7-positive circulating tumor cells detected by Epic's technology.
Researchers presented data suggesting that pharma companies are using basket studies to identify molecularly defined patient subsets who might benefit from their drugs.
Genome-wide association and other genetic studies hint at variants increasing subsequent neoplasm risk in individuals treated for cancer during childhood.
Tumor infiltrating cell adoptive cell therapy success in metastatic melanoma patients was associated with DNA methylation and histone acetylation changes.
Using blood samples from more than 15,000 individuals with advanced cancer, researchers identified somatic mutation patterns similar to those in TCGA's database.
SAP has released products for integrating and analyzing structured and unstructured clinical and genomic datasets, and supporting patient cohort analysis.