ASCO Liquid Biopsy Firms Eye Melanoma for Minimal Residual Disease Testing, Though Questions Remain Premium MRD assays show promise in immunotherapy response prediction with the potential to guide dose/treatment escalation with emerging adjuvant approaches. Personalized Residual Disease Assays Show Promise to Overcome Liquid Biopsy Challenges in Sarcomas Premium New data presented at the ASCO annual meeting this week showed that tumor-informed assays could detect emerging recurrence ahead of imaging. Early Adopters Share Experiences With Grail Cancer Test as Firm Faces New Clinical Questions Premium Real-world and trial data shored up evidence that the company's multi-cancer detection assay can guide follow-up assessment of patients with a positive result. Agendia's ImPrint Predicts Immunotherapy Response in Breast Cancer Subgroups Premium The 53-gene biomarker signature showed promise in predicting immunotherapy response in high-risk triple-negative and HR-positive breast cancer. Large Study of Early-Onset Colorectal Cancer Patients IDs Unique, Potentially Actionable Mutations In younger patients, HER2 mutations were more prevalent in those who had MSI-high/TMB-high tumors, while POLE mutations were more common in MSS/TMB-high tumors, researchers reported at ASCO. Jan 19, 2023 Colorectal Cancer Detection Data from CellMax Life Bodes Well for Planned FDA Bid Premium Aug 8, 2022 CAP Weighs in on dMMR, MSI Assays for Immunotherapy Patient Selection Premium Jun 22, 2022 Agendia Building Validation Data on ImPrint for Guiding Neoadjuvant Immunotherapy in Breast Cancer Premium Jun 15, 2022 MyOme Develops Cross-Ancestry Breast Cancer Polygenic Risk Score, Plans Product Launch Premium Jun 9, 2022 Sophia Genetics, GE Healthcare Begin DEEP-Lung-IV Data Collection, Technology Integration Premium Jun 8, 2022 New Data Suggests Liquid Biopsy Provides Early ID of Breast Cancer Patients Destined to Recur Premium Jun 7, 2022 African American Prostate Cancer Patients Get More VUS, Fewer Actionable Results, Studies Show Jun 7, 2022 Circulating Tumor DNA Utility in Post-Surgery Stage II Colon Cancer Cemented by New Data Premium Jun 6, 2022 UK Team Tests Whole-Genome, Targeted Sequencing in Family Practice Setting Apr 28, 2022 ASCO Guideline Update Expands, Clarifies Use of Breast Cancer Adjuvant Treatment Test Feb 22, 2022 Million Veterans Study Yields Prostate Cancer Risk Score With Promise for Improved Screening Premium Jan 26, 2022 Early Detection, MRD Test Data Get Optimistic Reception From GI Oncologists at ASCO Meeting Premium Jun 24, 2021 Indivumed Launches Bioinformatics Platform, Expands Cancer Drug Discovery Efforts Premium Jun 10, 2021 Molecular Profiling in Pediatric Cancer Trials Continues to Prove Valuable for Treatment Matching Premium Jun 9, 2021 Liquid Biopsy MRD Research at ASCO Showcases Uses in Variety of Tumor Types, Indications Jun 9, 2021 New Liquid Biopsy Data at ASCO Highlights Commercial Push Into Early Cancer Detection Jun 8, 2021 Liquid Biopsy-Guided EGFR Rechallenge Therapy Shows Benefit for Colorectal Cancer Patients Jun 8, 2021 ASCO Studies Highlight Systemic, Racial Inequities in Lung Cancer Biomarker Testing Premium Jun 7, 2021 Lucence Presents New Data on Liquid Biopsy for Late-Stage Cancer Monitoring, Treatment Guidance Premium Jun 7, 2021 Lynparza Benefit in Early BRCA-Mutated Breast Cancer Reignites Universal Genetic Testing Discussion Premium Load More Breaking News SARS-CoV-2 Variants of Concerns Evolved to Modify Host Immune Response, Multiomics Study Shows People in the News at GA4GH, Mercy BioAnalytics, Deepcell, One Biosciences New Products Posted to GenomeWeb: Clinical Microbiomics, Integra Biosciences, DNAstack, Bruker Angolan Namib Desert Population Analysis Uncovers New Ancestry Group With Deep Divergence Cedars-Sinai Sets Up $25M Single Cell Precision Medicine Center The Scan Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants. Small Study of Gene Editing to Treat Sickle Cell Disease In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms. Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema. Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.