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Lack of Standardization Across MDx Infectious Disease Tests Could Undermine Pandemic Preparedness
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Poor cross-compatibility may make it difficult to substitute components of automated sample processing and testing workflows in the case of shortages.

CDC Wastewater Surveillance Shifts to Public Health Labs With Planned Digital PCR Pathogen Panels
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The US Centers for Disease Control and Prevention will support dPCR platforms from Qiagen and Bio-Rad, as well as sequencing-based variant surveillance.

CDC Grants Could Indicate Shift Toward More Federal Funds for Public Health Lab Construction
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The agency announced last month that it provided $175 million to seven states and localities to either build, expand, or renovate public health laboratory space.

Labs Home in on SARS-CoV-2 Omicron Variant
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The Association of Public Health Laboratories is directing member labs to focus sequencing efforts on S-gene dropouts for the next week.

FDA to Harmonize COVID-19 Data with New Terminology Codes

The agency plans to work with a number of partners to develop codes that will describe tests and results to standardize data collection.

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The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.