AMP AMP-led Expert Groups Release Clinical CYP2D6 Pharmacogenomic Testing Recommendation The consensus guideline offers a two-tier categorization of alleles that are recommended for clinical CYP2D6 pharmacogenetic testing. AMP Cautions Against Using Cycle Threshold Values for PCR SARS-CoV-2 Tests in Clinical Practice Although a cycle threshold value may help determine patient prognosis and risk of transmission, there is limited data on making clinical decisions based on Ct values, AMP said. New AMP Survey Reports Insufficient Reimbursement for Analysis, Interpretation of MDx Test Results The survey found analysis, interpretation, and reporting requirements can take more than six hours per test but that reimbursement for tests doesn't account for this work. AMP Survey Finds Significant Decline in Molecular Cancer Testing Due to COVID-19 Pandemic Laboratory staffing and supply shortages limited patient access to cancer screening tests, and the pandemic decreased the development and validation of new tests. Ceres Nanosciences Hydrogel Technology Shows Promise for Capturing Circulating Tumor DNA Premium Ceres plans to develop its Nanotrap technology to isolate undetectable levels of circulating tumor DNA in blood samples from non-small cell lung cancer patients. Nov 24, 2020 Clinicians Face New Intervention Questions as Clonal Hematopoiesis Mutation Data Evolves Premium Nov 23, 2020 Broad Institute DepMap Project Could Lead to Development of New Cancer Drugs Premium Nov 20, 2020 Burning Rock Adds New Data Supporting Cancer Screening Liquid Biopsy, Automated NGS Products Premium Nov 20, 2020 Agena Bioscience Shows Off New Liquid Biopsy QC Assay at AMP; Expects January Launch Premium Nov 20, 2020 Illumina, IDbyDNA Flesh Out Sequencing-Based Respiratory Tests Premium Nov 19, 2020 AMP Panelists Highlight Need for Careful Lab Stewardship of Infectious Disease MDx Premium Nov 19, 2020 Putting Expanded Carrier Screening Into Practice Requires Considerations to Avoid Pitfalls Premium Nov 18, 2020 Lab Directors Discuss Unprecedented Challenges and Scrambling for Solutions During COVID-19 Pandemic Premium Nov 18, 2020 MSK Study Suggests Germline Tests May Miss Mosaic Cancer Risk Mutations in Some Patients Premium Nov 18, 2020 Lurie Children's Hospital Details Migration of Clinical Diagnostics Lab to hg38 Reference Genome Premium Nov 18, 2020 CNV Analyses May Uncover Mendelian Conditions in Undiagnosed Pediatric Patients Nov 17, 2020 Cepheid Developing New Target for BCR-ABL Test for Leukemia Patients Premium May 28, 2020 AMP SARS-CoV-2 Molecular Dx Survey Shows Supply Chain Issues Hampered Ramp Up of Testing May 6, 2020 AMP Working Group Recommends Alleles to Include in Warfarin Sensitivity Genotyping Assays Mar 16, 2020 House Passes Bill to Cover Coronavirus Testing with Emergency Use Authorization Feb 19, 2020 Cancer, Pathology Organizations Developing Clinical Guidelines for MMR, MSI Testing Nov 19, 2019 Paragon Genomics Discusses New Gene Fusion Detection Method, Cystic Fibrosis Panel Premium Nov 12, 2019 AMP Attendees Reflect on Uptake of Tumor Mutational Burden Amid Validation, Utility Questions Premium Nov 8, 2019 Illumina Unveils Liquid Biopsy Version of TSO 500 Panel, Highlights Early User Validations Premium Nov 7, 2019 Thermo Fisher Launches Genexus Sequencing System to Support Local Deployment of NGS Premium Load More Breaking News Pediatric Medulloblastoma Subgroups May Benefit from Lower-Dose Radiation Therapy Space Radiation Shows Limited Effects on Mammalian Sperm DNA, Fertility Bluestar Genomics Sues Former Consultant, Ludwig Institute for Cancer Research Over IP Ownership New Products Posted to GenomeWeb: 10x Genomics, Swift Biosciences, Agilent Technologies, More In Brief This Week: Quantum-Si, TGen, Yale, and More People in the News: New Appointments at Invitae, PGDx, Oxford Nanopore, PacBio, More The Scan Fertility Fraud Found Consumer genetic testing has uncovered cases of fertility fraud that are leading to lawsuits, according to USA Today. Ties Between Vigorous Exercise, ALS in Genetically At-Risk People Regular strenuous exercise could contribute to motor neuron disease development among those already at genetic risk, Sky News reports. Test Warning The Guardian writes that the US regulators have warned against using a rapid COVID-19 test that is a key part of mass testing in the UK. Science Papers Examine Feedback Mechanism Affecting Xist, Continuous Health Monitoring for Precision Medicine In Science this week: analysis of cis confinement of the X-inactive specific transcript, and more.