AMP Tests to Guide PARP Inhibitors Emerge as New Focus for Public-Private Harmonization Effort Premium Results from a homologous recombination deficiency assay concordance study led by Friends of Cancer Research were presented at the AMP annual meeting. Pathologists Evaluate Implementation of PGDx Comprehensive Genomic Profiling Kit Premium At the AMP annual meeting last week, two lab directors shared their experiences and discussed the assay's pros and cons in a company-sponsored workshop. Thermo Fisher Introduces Homologous Recombination Deficiency Score for Cancer Profiling Assay Premium The firm is also bringing its comprehensive genomic profiling assay for cancer to the Ion Torrent Genexus sequencing platform in the first half of 2023. UK Startup LEX Diagnostics Developing Ultra-Fast Low-Cost PCR for Infectious Disease Dx Premium At the AMP annual meeting this week, the company outlined its technology and vision for a speedy, low-cost, high-accuracy diagnostic. AMP, CAP Release Guidelines for Use of In Silico Approaches for Validating NGS Data Pipelines Labs should not let in silico data supplant physical specimens in bioinformatic validation and should understand the limitations of such data. Aug 26, 2022 AMP Publishes Recommendations for TPMT, NUDT15 Genotyping Assay Standardization Aug 25, 2022 Senate Bill Proposes Bringing Back Patents on Genes Premium Aug 8, 2022 CAP Weighs in on dMMR, MSI Assays for Immunotherapy Patient Selection Premium Apr 19, 2022 AMP Offers Recommendations to CMS, HHS to Prepare for Next Pandemic Oct 29, 2021 AMP Calls for Standards for Reporting Genetic, Genomic Test Data in EHRs Premium Jul 29, 2021 Association for Molecular Pathology Issues Guidelines to Promote Genetic Variant Data Sharing Jun 10, 2021 AMP-led Expert Groups Release Clinical CYP2D6 Pharmacogenomic Testing Recommendation Apr 21, 2021 AMP Cautions Against Using Cycle Threshold Values for PCR SARS-CoV-2 Tests in Clinical Practice Mar 16, 2021 New AMP Survey Reports Insufficient Reimbursement for Analysis, Interpretation of MDx Test Results Feb 23, 2021 AMP Survey Finds Significant Decline in Molecular Cancer Testing Due to COVID-19 Pandemic Dec 7, 2020 Ceres Nanosciences Hydrogel Technology Shows Promise for Capturing Circulating Tumor DNA Premium Nov 24, 2020 Clinicians Face New Intervention Questions as Clonal Hematopoiesis Mutation Data Evolves Premium Nov 23, 2020 Broad Institute DepMap Project Could Lead to Development of New Cancer Drugs Premium Nov 20, 2020 Burning Rock Adds New Data Supporting Cancer Screening Liquid Biopsy, Automated NGS Products Premium Nov 20, 2020 Agena Bioscience Shows Off New Liquid Biopsy QC Assay at AMP; Expects January Launch Premium Nov 20, 2020 Illumina, IDbyDNA Flesh Out Sequencing-Based Respiratory Tests Premium Nov 19, 2020 AMP Panelists Highlight Need for Careful Lab Stewardship of Infectious Disease MDx Premium Nov 19, 2020 Putting Expanded Carrier Screening Into Practice Requires Considerations to Avoid Pitfalls Premium Nov 18, 2020 Lab Directors Discuss Unprecedented Challenges and Scrambling for Solutions During COVID-19 Pandemic Premium Nov 18, 2020 MSK Study Suggests Germline Tests May Miss Mosaic Cancer Risk Mutations in Some Patients Premium Load More Breaking News New Products Posted to GenomeWeb: Qiagen, Thermo Fisher, Bionano Genomics, BillionToOne, More People in the News at Illumina Ventures, Element Biosciences, Epigenomics, Exagen, More Genomic Approaches Boost Rare Disease Diagnoses in Middle Eastern Patient Population GeneDx to Raise $150M in Public and Direct Stock Offerings In Brief This Week: T2 Biosystems, Novacyt, OpGen, Dante Genomics, Nautilus Biotechnology, More The Scan Self-Reported Hearing Loss in Older Adults Begins Very Early in Life, Study Says A JAMA Otolaryngology — Head & Neck Surgery study says polygenic risk scores associated with hearing loss in older adults is also associated with hearing decline in younger groups. Genome-Wide Analysis Sheds Light on Genetics of ADHD A genome-wide association study meta-analysis of attention-deficit hyperactivity disorder appearing in Nature Genetics links 76 genes to risk of having the disorder. MicroRNA Cotargeting Linked to Lupus A mouse-based study appearing in BMC Biology implicates two microRNAs with overlapping target sites in lupus. Enzyme Involved in Lipid Metabolism Linked to Mutational Signatures In Nature Genetics, a Wellcome Sanger Institute-led team found that APOBEC1 may contribute to the development of the SBS2 and SBS13 mutational signatures in the small intestine.