AMP Association for Molecular Pathology Issues Guidelines to Promote Genetic Variant Data Sharing The group drafted a series of recommendations for key stakeholders including clinical labs, database operations, policymakers, and researchers. AMP-led Expert Groups Release Clinical CYP2D6 Pharmacogenomic Testing Recommendation The consensus guideline offers a two-tier categorization of alleles that are recommended for clinical CYP2D6 pharmacogenetic testing. AMP Cautions Against Using Cycle Threshold Values for PCR SARS-CoV-2 Tests in Clinical Practice Although a cycle threshold value may help determine patient prognosis and risk of transmission, there is limited data on making clinical decisions based on Ct values, AMP said. New AMP Survey Reports Insufficient Reimbursement for Analysis, Interpretation of MDx Test Results The survey found analysis, interpretation, and reporting requirements can take more than six hours per test but that reimbursement for tests doesn't account for this work. AMP Survey Finds Significant Decline in Molecular Cancer Testing Due to COVID-19 Pandemic Laboratory staffing and supply shortages limited patient access to cancer screening tests, and the pandemic decreased the development and validation of new tests. Dec 7, 2020 Ceres Nanosciences Hydrogel Technology Shows Promise for Capturing Circulating Tumor DNA Premium Nov 24, 2020 Clinicians Face New Intervention Questions as Clonal Hematopoiesis Mutation Data Evolves Premium Nov 23, 2020 Broad Institute DepMap Project Could Lead to Development of New Cancer Drugs Premium Nov 20, 2020 Burning Rock Adds New Data Supporting Cancer Screening Liquid Biopsy, Automated NGS Products Premium Nov 20, 2020 Agena Bioscience Shows Off New Liquid Biopsy QC Assay at AMP; Expects January Launch Premium Nov 20, 2020 Illumina, IDbyDNA Flesh Out Sequencing-Based Respiratory Tests Premium Nov 19, 2020 AMP Panelists Highlight Need for Careful Lab Stewardship of Infectious Disease MDx Premium Nov 19, 2020 Putting Expanded Carrier Screening Into Practice Requires Considerations to Avoid Pitfalls Premium Nov 18, 2020 Lab Directors Discuss Unprecedented Challenges and Scrambling for Solutions During COVID-19 Pandemic Premium Nov 18, 2020 MSK Study Suggests Germline Tests May Miss Mosaic Cancer Risk Mutations in Some Patients Premium Nov 18, 2020 Lurie Children's Hospital Details Migration of Clinical Diagnostics Lab to hg38 Reference Genome Premium Nov 18, 2020 CNV Analyses May Uncover Mendelian Conditions in Undiagnosed Pediatric Patients Nov 17, 2020 Cepheid Developing New Target for BCR-ABL Test for Leukemia Patients Premium May 28, 2020 AMP SARS-CoV-2 Molecular Dx Survey Shows Supply Chain Issues Hampered Ramp Up of Testing May 6, 2020 AMP Working Group Recommends Alleles to Include in Warfarin Sensitivity Genotyping Assays Mar 16, 2020 House Passes Bill to Cover Coronavirus Testing with Emergency Use Authorization Feb 19, 2020 Cancer, Pathology Organizations Developing Clinical Guidelines for MMR, MSI Testing Nov 19, 2019 Paragon Genomics Discusses New Gene Fusion Detection Method, Cystic Fibrosis Panel Premium Nov 12, 2019 AMP Attendees Reflect on Uptake of Tumor Mutational Burden Amid Validation, Utility Questions Premium Nov 8, 2019 Illumina Unveils Liquid Biopsy Version of TSO 500 Panel, Highlights Early User Validations Premium Load More Breaking News Ancient DNA Analysis Highlights Three Ancestral Populations in Japan FDA Warns of Potential False Positives With Abbott SARS-CoV-2 Molecular Tests New Products Posted to GenomeWeb: Oxford Nanopore, Beckman Coulter, Thermo Fisher Scientific, More People in the News: New Appointments at Sema4, NHGRI, Dante Labs, Ancestry, More Thermo Fisher Scientific Expects 12 Percent Revenue Growth in 2022 In Brief This Week: Myriad Genetics, Danaher, Co-Diagnostics, and More The Scan For Those Thick Tiger Stripes Tigers in India with thick stripes harbor a genetic change, as Gizmodo reports. High GABA Tomatoes The Japan News reports that genome-edited tomatoes with higher GABA levels are now for sale in Japan. Approach for Inclusivity and Diversity A National Human Genome Research Institute team calls for the field to "adopt diversity as an ethos." Science Papers on Tumors Immune System Evasion; Drivers of Genomic Instability, Inflammation In Science this week: study of how tumors evade the adaptive immune system, and more.