Albert Einstein College of Medicine
At the inaugural International Conference on Newborn Sequencing (ICoNS) in Boston last week, researchers outlined plans from eight studies in the US, the UK, Europe, and Australia.
Single-Cell Sequencing Study Finds Increased Single-Nucleotide Mutation Rate in Lungs of Smokers
This mutation rate increased linearly until 23 pack-years of exposure before plateauing, suggesting there may be mechanisms limiting mutation accumulation.
The technique, called single-molecule mutation sequencing (SMM-seq), uses rolling circle amplification to increase the number of copies of parental strands used for sequencing.
Centenarian Exome Analysis Points to Conserved Longevity Pathways
Researchers found rare coding variants in conserved pathways that appear to be associated with longevity and potentially protect against aging.
Cervicovaginal Microbiomes of HPV-Infected Women Lead To Potential Pre-Cancer Marker
Profiling microbial communities in cervicovaginal samples from women carrying high-risk HPV strains, researchers found possible markers of pre-cancer progression.