Profiling microbial communities in cervicovaginal samples from women carrying high-risk HPV strains, researchers found possible markers of pre-cancer progression.
New research suggests that a set of common variants on chromosome 22 may influence heart defects associated with a condition called 22q11.2 deletion syndrome.
In Genome Biology this week: analysis of gut microbiomes from the Hispanic Community Health Study/Study of Latinos, collection of patient-derived tumor cells from gynecological cancers, and more.
Some of the mutational signatures the researchers observed were similar to ones previously seen in B cell tumors, underscoring the link between aging and cancer.
The assay uses a genomic DNA signature called the metastatic potential score derived from copy number alteration analysis of specific regions of the genome.
In Nature this week: a method called cis-X combines whole-genome and transcriptome sequencing data to identify regulatory noncoding variants, and more.
