Aarhus University
Polygenic Scores Have Low Portability Between Genetic Populations, UK Biobank-Based Study Finds
A polygenic score developed in a UK ancestry group had decreased predictiveness when applied to other genetic ancestry groups, including other European groups.
The company is positioning the blood-based test as an alternative to invasive chorionic villus sampling, the current standard in Denmark.
Anxiety GWAS, Mouse Model Experiments Lead to Potential New Drug Target
With a large genome-wide association study, researchers identified several significant associations in PDE4B, a gene with expression shifts in brain samples from stressed mice.
Neanderthal Allele Fragment Size, Mutational Signatures Suggest Shorter European Generations
Based on allele fragment sizes and mutational signatures, Europeans may have had shorter generation times than other populations, a Biology of Genomes speaker said.
Circulating Tumor DNA Forecasts Recurrence in Non-Metastatic Colorectal Cancer
Two new studies of stage I to III CRC suggest that the presence of ctDNA in the months after surgery or chemotherapy can help identify patients who go on to relapse.