Not Yet Perfected

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In a profile of Johns Hopkins University's Bert Vogelstein in Science, Jocelyn Kaiser says he and his co-PI Kenneth Kinzler have helped "lay the foundation of cancer genetics," work that now inspires other researchers to use genetics to predict cancer risk and develop personalized treatments. And yet, Kaiser adds, Vogelstein and Kinzler seem to spend most of their time these days being skeptical about these efforts. "Vogelstein seems to enjoy pricking balloons.

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