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NINDS Funds Salk Neuroscience Core Center

NEW YORK (GenomeWeb News) – The Salk Institute has been awarded a five-year, $4.5 million grant from the National Institute of Neurological Diseases and Stroke to start a center that will provide resources to support brain research involving genomics, bioimaging, and behavioral science.

The Neuroscience Core Center will use its funding to provide research support for genome manipulation, imaging, and behavioral studies. The genome manipulation core will help researchers develop genetically modified mice to be model organisms for studying neurological diseases, such as autism, schizophrenia, and Alzheimer's.

"Brain researchers are increasingly focused on the links between genes and behavior, exploring how genetics play a role in brain development, which is ultimately manifested in a person's ability to function," Dennis O'Leary, the Vincent J. Coates Professor of Molecular Biology at Salk and director of the planned center, said in a statement. "We can manipulate embryonic stem cells to make different types of mice that have genes altered to relate to specific diseases."

Salk Institute President William Brody said that the new center will "speed discovery of how genetic changes alter abilities such as motor function, learning, and memory."

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