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Vizgen Merscope Ultra Platform and MERFISH 2.0 Chemistry

Vizgen has launched the Merscope Ultra platform and MERFISH (multiplex, error-resistant fluorescence in situ hybridization) 2.0 Chemistry. Both will be commercially available in the second half of the year.

Merscope Ultra is a new high-plex in situ spatial multiomic analysis system that is capable of processing 3 cm2 of tissue on a single slide. The image processing speed of Merscope Ultra doubles that of the previous Merscope platform, Vizgen said. The system can also offer two different size flow cells enabling users to adjust reagent consumption based on the area imaged.

Vizgen said its MERFISH 2.0 chemistry leverages improved RNA anchoring and signal enhancement to increase MERFISH's sensitivity and reproducibility. The optimized chemistry enables broader sample compatibility, improving performance in archival formalin-fixed paraffin-embedded samples.