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Twist Bioscience TCR and CAR Libraries

Twist Bioscience has launched the Twist T-cell Receptor (TCR) and chimeric antigen receptor (CAR) libraries to enable researchers to rapidly create custom libraries to identify and develop next-generation cell therapies. These large and diverse libraries are made of up to 10,000 gene fragment combinations, enabling high-throughput screening and characterization of novel and known sequence variants for therapeutic discovery, Twist said. In these libraries, combinations of custom gene parts are shuffled to allow customers to test multiple elements at once, explore new combinations of variable binding regions, and select candidates with the greatest therapeutic potential, accelerating the discovery phase and expediting the timeline to the clinic, the company said.

The Scan

ChatGPT Does As Well As Humans Answering Genetics Questions, Study Finds

Researchers in the European Journal of Human Genetics had ChatGPT answer genetics-related questions, finding it was about 68 percent accurate, but sometimes gave different answers to the same question.

Sequencing Analysis Examines Gene Regulatory Networks of Honeybee Soldier, Forager Brains

Researchers in Nature Ecology & Evolution find gene regulatory network differences between soldiers and foragers, suggesting bees can take on either role.

Analysis of Ashkenazi Jewish Cohort Uncovers New Genetic Loci Linked to Alzheimer's Disease

The study in Alzheimer's & Dementia highlighted known genes, but also novel ones with biological ties to Alzheimer's disease.

Tara Pacific Expedition Project Team Finds High Diversity Within Coral Reef Microbiome

In papers appearing in Nature Communications and elsewhere, the team reports on findings from the two-year excursion examining coral reefs.