Twist Bioscience Human Methylome Panel

Twist Bioscience has launched its human methylome panel, a target enrichment assay for next-generation sequencing. The 123-Mb panel uses hybrid capture to detect the most recently identified and relevant CpG methylation regions in the genome, covering 84 percent of CpG island sites. It achieves depth of coverage of 90 percent of bases at 30x coverage with 95 percent on-target rate for probes as well as high uniformity across target regions.