Twist Bioscience FlexPrep Ultra-High Throughput Library Preparation Kit

Twist Bioscience has launched its FlexPrep Ultra-High Throughput Library Preparation Kits, designed to accelerate the adoption of next-generation sequencing by microarray users in population and agricultural genomics. The kit improves upon standard enzymatic fragmentation library preparation methods with the introduction of a novel "Normalization by Ligation" (NBL) technology, which eliminates the need for time-consuming upfront sample quantitation, and enables sample pooling and multiplexing early in the workflow, Twist said. Researchers can run up to 1,152 samples in a single 96-well plate sequencing run and, compared to processing samples individually, FlexPrep reduces consumables use 12-fold and reduces the number of pipette tips from more than 17,000 to less than 4,000, the company noted. The FlexPrep UHT kit can also be paired with Twist's custom target enrichment panels for tunable and uniform coverage of genomic regions of interest. In addition, Twist said it is collaborating with Gencove to offer analysis solutions to FlexPrep UHT customers to understand their data and deliver fast, cost-effective, and accurate genotyping results.