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Twist Bioscience and Pacific Biosciences 'Twist Alliance' Panels for HiFi Sequencing

Twist Bioscience and Pacific Biosciences have launched a portfolio of off-the-shelf target enrichment panels for long-read sequencing.

The firms collaborated with researchers to develop two Twist Alliance panels. One covers nearly 400 medically relevant genes in genomic regions that are challenging to sequence with short-read methods, including SMN1, SMN2, GBA, and LPA. The other captures 50 genes relevant for pharmacogenomics. Customers may also develop fully customizable panels, the companies said.

The Scan

Open Pediatric Brain Tumor Atlas Team Introduces Genomic Data Collection, Analytical Tools

A study in Cell Genomics outlines open-source methods being used to analyze and translate whole-genome, exome, and RNA sequence data from the Pediatric Brain Tumor Atlas.

Neurological Outcomes Linked to Innate Immune Features After Cardiac Arrest

Researchers reporting in Med dig into immune features found a few hours after cardiac arrest that correspond with neurological outcomes.

Mouse Study Finds Circadian Rhythm-Related Gene Expression Changes Linked to Sleep Apnea

A paper in PLOS Biology reveals tissue-specific circadian rhythm and gene expression patterns in an intermittent hypoxia-based mouse model of obstructive sleep apnea.

Polygenic Risk Score to Predict Preeclampsia, Gestational Hypertension in Pregnant Women

Researchers in Nature Medicine provide new mechanistic insights into the development of hypertensive disorders of pregnancy, which may help develop therapeutics.