Tethis See.d Blood Sample Prep Platform

Tethis, a Milan, Italy-based liquid biopsy technology firm, has launched See.d, a universal blood sample prep platform for liquid biopsy. The research-use-only platform performs completely automated and standardized preparation of a blood sample at the point of collection. The platform processes fresh blood collected in EDTA tubes, and automates separation of plasma from cellular fraction, red blood cell lysis and removal, white blood cell dispensation and fixation on SBS slides, and plasma recovery in tubes. At the end of the process, the SBS slides with a fixed monolayer of all white blood cells is made available, and the relative plasma aliquot is provided in a separate tube, Tethis said. The SBS slides are compatible with all analytical pathology techniques, including cytology, immunocytochemistry, immunofluorescence, and fluorescence in situ hybridization for morphological and biomarker-based analysis, the company added. In addition, the plasma is stable for several days and ready for cell-free DNA extraction without any further centrifugation steps, the company said.

Tethis is currently validating the platform for CE-IVD marking, developing liquid biopsy tests, and seeking partnerships with diagnostic and drug-development companies, it said.