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Roche Kapa HyperExome V2 Probes

Roche has launched its Kapa HyperExome V2 Probes, a whole-exome sequencing panel that provides a key update to the company's Kapa HyperCap Target Enrichment portfolio. The new panel covers recent versions of the ACMGv3.1, RefSeq, CCDS, ClinVar, Ensembl and COSMIC genomic databases within a compact capture target of 43.2 Mb with low sequencing requirements, the company notes on its website. The new T2T (telomere-to-telomere) genome assembly was utilized as part of the design process to identify potentially problematic regions not apparent in the GRCh38 genome assembly, Roche said. The new kit has been optimized using real-world samples in the Kapa HyperCap Workflow including the Kapa EvoPlus, Kapa HyperPlus and Kapa HyperPrep Kits to efficiently cover hard-to-capture regions, the company added.