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Roche Kapa HyperCap Design Share Non-Hodgkin Lymphoma Panel

Roche has launched its Kapa HyperCap Design Share Non-Hodgkin Lymphoma Panel to allow researchers to detect and perform longitudinal analyses on cell-free circulating tumor DNA. It covers single nucleotide variants in coding and untranslated regions of 383 genes, plus additional intergenic regions for a total capture size of 341 kb. These regions are enriched in genomic alterations associated with non-Hodgkin lymphoma. The panel is available for research use only.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.