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Qiagen QIAseq Normalizer Kit

Qiagen has launched a kit for nomalizing DNA concentrations across next-generation sequencing libraries. The kit can normalize different library types over a range of concentrations in 30 minutes. The high-throughput method has an optimized protocol for parallel normalization of 96 samples, and is also automation-friendly and works without hazardous chemicals.

Researchers can use QIAseq Normalizer with Qiagen’s existing QIAseq library prep solutions to streamline NGS workflows, or with a range of DNA- and RNA-library prep workflows from other providers for Illumina sequencing platforms. QIAseq Normalizer results in double-stranded DNA libraries, which are also compatible with long-term storage.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.