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Qiagen NeuMoDx MPXV Test Strip

Qiagen has launched the NeuMoDx MPXV Test Strip, a research-use-only multiplex assay that identifies both clades of monkeypox. The test comprises DNA extraction from lesion fluid swabs to isolate target nucleic acids followed by real-time PCR. It is designed as a dual-target assay to reduce false negatives, and provides results in about 70 minutes running on Qiagen's NeuMoDx and NeuMoDx 288 Molecular Systems. Test strips and core reagents and consumables are ready to use, can remain on board a NeuMoDx system for a minimum of seven days, and can be loaded while the system is operating, Qiagen noted.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.