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PCR Biosystems Air-Dryable Probe 1-Step Mix

PCR Biosystems has launched Air-Dryable Probe 1-Step Mix, an all-in-one, air-dryable 4x RT-qPCR reagent mix for the detection of RNA and DNA sequences. The kits allow developers to use standard lab ovens to dry reagents in 80 minutes as an alternative to lyophilization. They comprise a glycerol-free 4x qPCR mix with hot start Taq polymerase, dNTPs, MgCl₂, and other reagents for drying without activity loss. A more stable version of UltraScript reverse transcriptase and RiboShield RNase inhibitor are also added, providing a single-tube format. Kits can be used for both RNA and DNA detection, and dried assays are stable for three months at 37°C.

The Scan

Machine Learning Helps ID Molecular Mechanisms of Pancreatic Islet Beta Cell Subtypes in Type 2 Diabetes

The approach helps overcome limitations of previous studies that had investigated the molecular mechanisms of pancreatic islet beta cells, the authors write in their Nature Genetics paper.

Culture-Based Methods, Shotgun Sequencing Reveal Transmission of Bifidobacterium Strains From Mothers to Infants

In a Nature Communications study, culture-based approaches along with shotgun sequencing give a better picture of the microbial strains transmitted from mothers to infants.

Microbial Communities Can Help Trees Adapt to Changing Climates

Tree seedlings that were inoculated with microbes from dry, warm, or cold sites could better survive drought, heat, and cold stress, according to a study in Science.

A Combination of Genetics and Environment Causes Cleft Lip

In a study published in Nature Communications, researchers investigate what combination of genetic and environmental factors come into play to cause cleft lip/palate.