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New England Biolabs WarmStart Fluorescent LAMP/RT-LAMP Kit and Master Mix

New England Biolabs has released the WarmStart Multi-Purpose LAMP/RT-LAMP 2X Master Mix and the WarmStart Fluorescent LAMP/RT-LAMP Kit. The products allow researchers to perform efficient, high-throughput detection of nucleic acids using a variety of amplification detection methods. The master mix has dUTP and UDG for carryover prevention, can be used with highly buffered and acidic samples, and supports multiple detection methods including turbidity detection and non-pH-based colorimetric detection. The kit is a fully buffered Multi-Purpose LAMP/RT-LAMP 2X Master Mix and a fluorescent dye in one package.

The Scan

UK Pilot Study Suggests Digital Pathway May Expand BRCA Testing in Breast Cancer

A randomized pilot study in the Journal of Medical Genetics points to similar outcomes for breast cancer patients receiving germline BRCA testing through fully digital or partially digital testing pathways.

Survey Sees Genetic Literacy on the Rise, Though Further Education Needed

Survey participants appear to have higher genetic familiarity, knowledge, and skills compared to 2013, though 'room for improvement' remains, an AJHG paper finds.

Study Reveals Molecular, Clinical Features in Colorectal Cancer Cases Involving Multiple Primary Tumors

Researchers compare mismatch repair, microsatellite instability, and tumor mutation burden patterns in synchronous multiple- or single primary colorectal cancers.

FarGen Phase One Sequences Exomes of Nearly 500 From Faroe Islands

The analysis in the European Journal of Human Genetics finds few rare variants and limited geographic structure among Faroese individuals.