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New England Biolabs E5hmC-seq

New England Biolabs has launched the NEBNext Enzymatic 5hmC-seq Kit (E5hmC-seq), a novel enzyme-based method for the specific detection of 5hmC sites. According to the company, the approach enables high yields and high-quality data, with an input range of 100 picograms to 200 nanograms.

The kit includes the reagents required for E5hmC-seq conversion and library preparation compatible with Illumina sequencing. Index primers for multiplexing are available separately, the company said. A conversion module is also available for applications beyond library prep.