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Natera Donor Quantity Score

Natera launched the Donor Quality Score (DQS), a new feature for its Prospera Heart product that normalizes for background total cell-free DNA. Prospera Heart with DQS combines the traditional donor cfDNA measurement and the new DQS into a two-threshold algorithm, delivering a single risk assessment for both antibody-mediated rejection and acute cellular rejection, with improved sensitivity, specificity, and negative predictive value, compared to traditional donor cfDNA fraction alone, Natera said.