MRC Holland SALSA DigitalMLPA Probemix D001 Hereditary Cancer Panel 1

MRC Holland has launched an update to its SALSA DigitalMLPA Probemix D001 Hereditary Cancer Panel 1. The original assay detected copy number variants in 28 genes and five variants associated with hereditary cancer risk. The updated version has new probes and modifications to existing probes to improve the assay's performance, including probes targeting an exon 2-6 inversion in the MSH2 gene, which is associated with Lynch syndrome. The assay has a turnaround time of 48 to 72 hours and requires at least 20 ng of DNA input per reaction.