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Molecular Instruments HCR RNA-CISH

Molecular Instruments (MI), a biotech spinout of the California Institute of Technology, has launched HCR RNA-CISH to enhance automated chromogenic in situ hybridization (ISH) workflows that depend on RNAscope. The HCR RNA-CISH kits provide better performance than any existing chromogenic in situ hybridization approach with double the turnaround time and half the cost, the company said. HCR RNA-CISH also features native support for IHC codetection and full compatibility with all major automation platforms, the company added.

The Scan

Machine Learning Helps ID Molecular Mechanisms of Pancreatic Islet Beta Cell Subtypes in Type 2 Diabetes

The approach helps overcome limitations of previous studies that had investigated the molecular mechanisms of pancreatic islet beta cells, the authors write in their Nature Genetics paper.

Culture-Based Methods, Shotgun Sequencing Reveal Transmission of Bifidobacterium Strains From Mothers to Infants

In a Nature Communications study, culture-based approaches along with shotgun sequencing give a better picture of the microbial strains transmitted from mothers to infants.

Microbial Communities Can Help Trees Adapt to Changing Climates

Tree seedlings that were inoculated with microbes from dry, warm, or cold sites could better survive drought, heat, and cold stress, according to a study in Science.

A Combination of Genetics and Environment Causes Cleft Lip

In a study published in Nature Communications, researchers investigate what combination of genetic and environmental factors come into play to cause cleft lip/palate.