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Miroculus Miro Canvas

Miroculus has launched a new digital microfluidics platform that can carry out on-demand automation of complex next-generation sequencing sample preparation protocols. The instrument was unveiled during the Advances in Genome Biology and Technology meeting in February 2020, but it wasn't commercially launched until this week. According to the company, the platform is capable of digitally encoding, fully automating, and running all NGS prep protocols, even complex ones, with a universal cartridge and without requiring any hardware changes between runs. With its ability to simplify, automate, and miniaturize complex NGS library prep, Miroculus said the platform is well-suited for laboratories that do not run a high volume of sequencing samples and want improved control over sample processing.

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.